Complications of non-compaction of the left ventricular myocardium in a paediatric population: a prospective study

Abstract

When prospectively evaluated, NCVM appears to have been previously under-diagnosed. Whereas arrhythmias and thrombo-embolic events were rare, CHF was frequently found. An equally aggressive anticongestive treatment regimen would seem indicated for both the NCVM subgroups.

A patient with abnormalities of the coronary arteries and non-compaction of the left ventricular myocardium resulting in ischaemic heart disease symptoms

“…Initially it was considered as a rare condition, but nowadays due to the wide using of imaging techniques, is recognised more frequently and often accidentally when patients undergo cardiovascular investigation for other reasons. According to the literature the prevalence of non-compacted cardiomyopathy in the general population ranges from 0.014% to 1.3% [10,14]. However it seems that the prevalence of LVNC may be underestimated because of its occurrence also in patients without clinical symptoms or because of subjective assessment of echocardiography findings.…”

“…Current data suggest better outcomes, particularly when the disease is asymptomatic or early recognised [10,11,14,16]. Conditions deteriorating the prognosis embrace significant advancement of HF symptoms (III or IV NYHA class), sustained ventricular tachycardia and advanced age.…”

Miocardiopatia não compactada: uma visão atual

“…Some cardiac abnormalities may be associated with NCC: • Presence of Ebstein's anomaly, bicuspid aortic valve and transposition of great vessels 16,17 . Patients with NCC may also have a ventricular septal defect 18 .…”

En 11 måneder gammel jente med gjentatte luftveisinfeksjoner

“…I pediatrisk sammenheng finnes det en del publiserte kasuistikker samt seks kasusstudier omfattende totalt 171 barn med manglende modning av ventrikkelmyokard, omtalt av Lilje og medarbeidere (7). Som tilfellet er med hjertesvikt er bredden av symptomer og funn stor ved manglende modning av ventrikkelmyokard hos barn.…”

“…Dessuten er mange barn med tilstanden helt uten symptomer. Hos 5 220 barn henvist til kardiologisk utredning ved et barnekardiologisk senter i Hamburg ble en hyppighet på 1,25 % (66 barn) av manglende modning av ventrikkelmyokard rapportert (7). I samme studie viste Lilje og medarbeidere at 62 % av barna med manglende modning av ventrikkelmyokard hadde andre medfødte hjerteanomalier i tillegg.…”