Complications of head and neck radiation therapy and their management

Engelmeier, Robert L.; King, Gordon E.

doi:10.1016/0022-3913(83)90314-1

Cited by 62 publications

(29 citation statements)

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“…1939 wurde der Begriff der Strahlenkaries durch del Regato [32] im angloamerikanischen Bereich eingeführt. Zwei Pathomechanismen der Strahlenkaries wurden diskutiert: einerseits die indirekte Wirkung über die Radioxerostomie [5,8,32,35] und die damit einhergehenden mikrobiologischen und funktionellen Veränderungen innerhalb der Mundhöhle [3,4], andererseits eine direkte radiogene Wirkung auf die Zahnhartsubstanz, insbesondere den Schmelz [2,26,27,30,41,42,48]. Neuere Untersuchungen belegen einen synergistischen Kombinationsschaden [45] aus indirekter Wirkung der Radioxerostomie und direkter radiogener Schädigung an der Schmelz-Dentin-Grenze als Locus minoris resistentiae [11,28,29].…”

Section: Introductionunclassified

Chronische Strahlenfolgen an den Zahnhartgeweben (“Strahlenkaries”) Klassifikation und Behandlungsansätze

Grötz

Riesenbeck²,

Brahm

et al. 2001

Strahlenther Onkol

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The documentation of early radiation effects on dental hard tissues seems to be neglectable. On the other hand the documentation of Late radiation effects has a high clinical impact. The identification of an initial lesion at the high-risk areas of the neck and incisal part of the tooth can lead to a successful therapy as a major prerequisite for orofacial rehabilitation. An internationally standardized documentation is a basis for the evaluation of the side effects of radiooncotic therapy as well as the effectiveness of protective and supportive procedures.

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Section: Introductionunclassified

Chronische Strahlenfolgen an den Zahnhartgeweben (“Strahlenkaries”) Klassifikation und Behandlungsansätze

Grötz

Riesenbeck²,

Brahm

et al. 2001

Strahlenther Onkol

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“…These sequelae predispose the patient to long-term morbidity from caries, plaque, gingival disease, alveolar bone resorption, and poor nutrition [16][17][18][19].…”

Section: Discussionmentioning

confidence: 99%

Dental abnormalities in long‐term survivors of head and neck rhabdomyosarcoma

Kaste

Hopkins

Bowman

1995

Med. Pediatr. Oncol.

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To define the long-term dental sequelae of therapy for childhood rhabdomyosarcoma of the head and neck, and to identify factors in their development, we retrospectively reviewed the serial panoramic radiographs and clinical records of 22 survivors of head or neck rhabdomyosarcoma who had been followed for at least 5 years. Patients were divided into four groups based upon age at the time of therapy and three groups based upon radiation doses. All patients had received similar multiagent chemotherapy. Dental sequelae of oncotherapy occurred in over half of the long-term survivors of head and neck rhabdomyosarcoma. The abnormalities comprised root stunting in 54%, microdontia in 23%, and hypodontia in 50% of patients; 36% had multiple abnormalities. Microdontia and multiple abnormalities were more prevalent in patients treated at the earliest age, and abnormalities tended to be more prevalent with increasing doses of radiation. Five patients (23%) developed severe cosmetic and/or functional sequelae necessitating surgical and/or orthodontic intervention. The high frequency of dental sequelae we observed suggests that meticulous long-term dental and radiographic follow-up are needed. Early detection and treatment of the complications of therapy will expedite their correction and minimize morbidity.

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“…however, may take from 1 to 2 years or never return to normal levels if the parotid glands are involved 1,29 .…”

Section: Hyposialiamentioning

confidence: 99%

Oral complications in patients receiving head and neck radiation therapy: a literature review

Sari¹,

Nasiloski

Gomes

2014

RGO, Rev. Gaúch. Odontol.

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Oral cancer is a relatively common disease worldwide and its incidence rate has increased over the years. In Brazil, thousands RESUMOO câncer bucal é uma doença relativamente comum a nível mundial e que vem aumentando a sua incidência ao longo dos anos. No Brasil, milhares de novos casos surgem e o cirurgião-dentista é o profissional que precisa estar preparado para diagnosticar, prevenir, intervir e orientar os pacientes quanto a doença, seu tratamento e as complicações inerentes ao mesmo. Não existe, atualmente, uma forma de tratamento sistêmico para o câncer que tenha a capacidade de destruir as células alteradas, sem causar dado ou a morte das células normais. A cirurgia combinada com a radioterapia é uma das formas mais comuns para tratamento dos tumores malignos de cabeça e pescoço. Essa modalidade de tratamento tem obtido altos índices de cura e sobrevida aos pacientes, porém, os efeitos colaterais existentes são graves e capazes de provocar morbidade aos pacientes, diminuindo a sua qualidade de vida. Desse modo, o objetivo do trabalho é realizar uma revisão de literatura sobre as principais complicações decorrentes do tratamento radioterápico, enfatizando a conduta do cirurgião-dentista frente a estas alterações.

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Complications of head and neck radiation therapy and their management

Cited by 62 publications

References 0 publications

Chronische Strahlenfolgen an den Zahnhartgeweben (“Strahlenkaries”) Klassifikation und Behandlungsansätze

Chronische Strahlenfolgen an den Zahnhartgeweben (“Strahlenkaries”) Klassifikation und Behandlungsansätze

Dental abnormalities in long‐term survivors of head and neck rhabdomyosarcoma

Oral complications in patients receiving head and neck radiation therapy: a literature review

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