Complications of coeliac disease

Medullary carcinoma of the small bowel

“…Two of our patients had CD. The association between different neoplasms and CD is well established, although the incidence of complicated CD is low . Patients have an increased risk of developing malignancy in relation to the age at diagnosis of CD.…”

“…The association between different neoplasms and CD is well established, although the incidence of complicated CD is low. 5,15,16 Patients have an increased risk of developing malignancy in relation to the age at diagnosis of CD. While delayed diagnosis has been shown to increase cancer risk, a gluten-free diet may have a protective effect [15].…”

“…4 Furthermore, CD patients are considered to have an increased risk of developing malignancy, in particular T cell lymphoma, but also small bowel cancer. 5 In this study, we present three cases of medullary small bowel carcinoma. In two patients the tumours developed against a background of CD.…”

“…This results in lymphocytic infiltration within the epithelium, crypt hyperplasia and villous atrophy . Furthermore, CD patients are considered to have an increased risk of developing malignancy, in particular T cell lymphoma, but also small bowel cancer …”

Going Beyond Gluten-Free

“…3 Once diagnosed, treatment requires lifelong adherence to a strict gluten-free diet and failure to do so places patients at risk of multiple health concerns, including suboptimal growth, progressive osteoporosis, enteropathy-associated T-cell lymphoma, and shortened life expectancy. 3,4 Thus, timely diagnosis and treatment, with regular follow-up to ensure compliance, are essential for the long-term health and well-being of all who have CD.…”