Complications of Axillary Lymph Node Dissection in Treatment of Early Breast Cancer: A Comparison of MRM and BCS

Brar, Preetinder; Jain, Satish; Singh, Iqbal

doi:10.1007/s13193-011-0078-2

Cited by 22 publications

(15 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, complications such as depression, contraction deformity, seroma, hematoma, and infection are relatively common in BCS when a relatively large amount of tissue is excised [6,7]. In recent years, several oncoplastic approaches have been implemented to increase the maximum amount of tissue that can be resected, while still achieving favorable cosmetic results and minimizing the risk of complications.…”

Section: Introductionmentioning

confidence: 99%

Retrospective review of 108 breast reconstructions using the round block technique after breast-conserving surgery: Indications, complications, and outcomes

Kim

et al. 2020

Arch Plast Surg

View full text Add to dashboard Cite

Background Several oncoplastic approaches have been implemented in recent years to enhance cosmetic results and to reduce complications. The round block technique is a volume displacement technique for breast reconstruction after breast-conserving surgery (BCS). However, its indications are currently limited according to tumor location, and its cosmetic results and complications have not been clearly established. We hypothesized that the round block technique could produce favorable cosmetic results without major complications regardless of tumor location or nipple-tumor distance, below a certain resected tumor volume and tumor-breast volume ratio.Methods All breast reconstructions using the round block technique after BCS were included in this analysis. Patients’ data were reviewed retrospectively to investigate complications during follow-up, and clinical photos were used to evaluate cosmetic results. The relationships of tumor location, nipple-tumor distance, tumor volume, and the tumor-breast volume ratio with cosmetic results were investigated.Results In total, 108 breasts were reconstructed. The mean resected tumor volume was 30.2±15.0 mL. The cosmetic score was 4.5±0.6 out of 5. Tumor location, nipple-tumor distance, tumor volume, tumor-breast volume ratio, radiotherapy, and chemotherapy had no significant effects on cosmetic results or complications. There were no major complications requiring reoperation.Conclusions Breast reconstruction using the round block technique after BCS can lead to good cosmetic results without major complications regardless of the tumor location, nipple-tumor distance, radiotherapy, or chemotherapy. Below the maximum tumor volume (79.2 mL) and the maximum tumor-breast volume ratio (14%), favorable results were consistently obtained.

show abstract

Section: Introductionmentioning

confidence: 99%

Retrospective review of 108 breast reconstructions using the round block technique after breast-conserving surgery: Indications, complications, and outcomes

Kim

et al. 2020

Arch Plast Surg

View full text Add to dashboard Cite

show abstract

“…At one year, 39% of these patients reported persistent ipsilateral arm pain. Other studies have compared the prevalence of pain within the larger context of “arm and shoulder morbidities” in patients who had breast conserving surgery versus mastectomy (Carpenter, et al, 1999; Nesvold, Dahl, Lokkevik, Marit Mengshoel, & Fossa, 2008; Vilholm, Cold, Rasmussen, & Sindrup, 2008); sentinel lymph node biopsy (SNLB) versus an axillary lymph node dissection (ALND) (Andersen, et al, 2013; Brar, Jain, & Singh, 2011; Haid, et al, 2002; Langer, et al, 2007; Ronka, von Smitten, Tasmuth, & Leidenius, 2005; Vilholm, et al, 2008); and following receipt of radiation therapy (RT) (Deutsch & Flickinger, 2001; Hopwood, et al, 2010; Vilholm, et al, 2008). As noted by Andersen and Kehlet (2011), while the majority of studies reported no differences in arm pain between breast conserving surgery and mastectomy, these findings need to be interpreted with caution because the nociceptive effect of RT was not evaluated.…”

Section: Introductionmentioning

confidence: 99%

Identification of patient subgroups and risk factors for persistent arm/shoulder pain following breast cancer surgery

Miaskowski

Paul

Cooper

et al. 2014

European Journal of Oncology Nursing

View full text Add to dashboard Cite

Purpose In this prospective, longitudinal study, we extend our findings on persistent breast pain in patients (n=398) following breast cancer surgery and evaluate the prevalence and characteristics of persistent pain in the arm/shoulder In addition, differences in the severity of common symptoms and quality of life outcomes measured prior to surgery, among the arm pain classes, were evaluated. Methods and sample Patients were recruited from Breast Care Centers located in a Comprehensive Cancer Center, two public hospitals, and four community practices. Patients were assessed prior to and monthly for six months following breast cancer surgery. Results Using growth mixture modeling, patients were classified into no (41.6%), mild (23.6%), and moderate (34.8%) arm pain classes based on ratings of worst arm/shoulder pain. Compared to the no pain class, patients in the moderate pain class were significantly younger, had a higher body mass index, and were more likely to report preoperative breast pain and swelling in the affected breast. In addition, patients in the moderate pain class reported higher levels of depression, anxiety, and sleep disturbance than the no pain class. Conclusions Findings suggest that approximately 35% of women experience persistent levels of moderate arm/shoulder pain in the first six months following breast cancer surgery. Moderate arm/shoulder pain is associated with clinically meaningful decrements in functional status and quality of life.

show abstract

“…Moreover, in our series, screened women had four times more often sentinel node excision instead of axillary node dissection and five times less often chemotherapy than symptomatically diagnosed women. This results in fewer side effects such as arm stiffness, edema, pain and impaired movements, lower risk of neurotoxicity, cardiomyopathy and thromboembolism [15][16][17][18].…”

Section: Discussionmentioning

confidence: 99%

Associated Morbidity in Screened and Diagnosed Breast Cancer Patients: A Retrospective Study

Diane¹,

C²,

Roche³

2021

austiniobstetgynecol

View full text Add to dashboard Cite

Introduction: Breast Cancer (BC) screening has been associated with reduced mortality and morbidity. This study compares tumor characteristics and treatment morbidity in screened versus diagnosed women. Materials and Methods: This retrospective study, conducted between 2010 and 2013, included 666 BC screened or diagnosed patients. We compared patients and tumors characteristics and received treatments. We also analyzed the results after excluding patients at risk of BC and conducted a multivariate analysis to assess odds ratios (OR). Results: Screened women had smaller tumors (16.5 vs. 22.6 mm, p<0.001), of lower grade (p<0.001) with a lower Proliferation Index (PI) (p<0.001) than diagnosed women. Screened women were more frequently treated using conservative surgery (82.8% vs. 59.7%, p<0.001), needed less often axillary dissection (15.1% vs. 35.4%, p<0.001) and less often chemotherapy (20.8% vs. 48.3% p<0.001) than diagnosed women. In the multivariate analysis after adjustment for age and BC history, diagnosed women had increased (OR: 4.79, 95% IC: 3.19-7.18) risk to be administered chemotherapy and to undergo axillary dissection (OR: 4.18, 95% IC: 1.56-11.17) than screened women. Conclusion: Patients should be informed about the benefits in terms of morbidity that screening confers to them.

show abstract

Complications of Axillary Lymph Node Dissection in Treatment of Early Breast Cancer: A Comparison of MRM and BCS

Abstract: ALND is part of primary management of breast cancer.

Cited by 22 publications

References 40 publications

Retrospective review of 108 breast reconstructions using the round block technique after breast-conserving surgery: Indications, complications, and outcomes

Retrospective review of 108 breast reconstructions using the round block technique after breast-conserving surgery: Indications, complications, and outcomes

Identification of patient subgroups and risk factors for persistent arm/shoulder pain following breast cancer surgery

Associated Morbidity in Screened and Diagnosed Breast Cancer Patients: A Retrospective Study

Contact Info

Product

Resources

About