Complications in immediate breast reconstruction after mastectomy

Abstract

A significant proportion of the patients receiving IBR developed reconstruction failure. Multivariate analysis identified three variables related to this complication, two of which were known before the intervention.

Breast reconstruction and adjuvant therapy: A systematic review of surgical outcomes

“…The differences in these studies may be partially due to the heterogeneity in treatment protocols and makes it difficult to draw strong conclusions. In terms of overall surgical success, the majority of studies indicate that adjuvant chemotherapy is not associated with increased complications or reconstructive failures [44,47,48,50,65,67]. This study has suggested that there are no significant contraindications to breast reconstruction in the setting of adjuvant chemotherapy.…”

“…The weighted mean of reported total complication rates was 35.5%. Thirty‐five articles included complications and/or reconstruction failures in device‐based reconstructions . Twenty‐seven articles included complications or reconstructive failures in autologous reconstructions .…”

“…Eight studies (566 patients) reported total complication rates or reconstructive failure rates that ranged from 16-54% and 0-32%, respectively [6,44,47,48,50,[65][66][67]. Six studies (435 patients) demonstrated no increase in the rate of complications or reconstructive failures when compared to cohorts not receiving adjuvant chemotherapy [44,47,48,50,65,67]. In a single study, an increase in reconstructive failure and overall complication rate was noted in 41 patients that had adjuvant chemotherapy [6].…”

A Prospective Study of Immediate Breast Reconstruction with Laser-Assisted Indocyanine Green Angiography

“… 18 , 19 Infection is most strongly associated with the eventual removal of the tissue expander or implant. 20 – 22 Such complications are a source of significant morbidity and may lead to delay in oncologic therapies and/or reconstructive failure rates of 5–20%. 20 …”

“… 20 – 22 Such complications are a source of significant morbidity and may lead to delay in oncologic therapies and/or reconstructive failure rates of 5–20%. 20 …”