Abstract:The complications of cerebral angiography have been recorded in 1509 examinations with metrizoate (Isopaque Cerebral) and in 1000 examinations with iohexol (Omnipaque). The frequency of complications was 2.0 percent for metrizoate and 1.3 percent for iohexol. Permanent sequelae were seen in 4 patients, 3 in the metrizoate and one in the iohexol group. One of these patients died, probably from thromboembolism. Blood coagulation parameters were studied during the angiography in 22 patients and only minor, probab… Show more
“…Unfortunately, this question was not addressed in a subsequent paper. 30 The authors incidentally found no significant difference in side effects between the different contrast media.…”
We review the eight prospective and seven retrospective studies from which it is possible to derive the complication rate of conventional cerebral angiography for patients with mild ischemic cerebrovascular disease who are potential candidates for carotid endarterectomy. Three studies of intravenous and one of intra-arterial digital subtraction angiography are also examined. An overview of the results suggests that the risk of a neurological complication (TIA or stroke) is about 4% and that a permanent neurological deficit (disabling stroke) occurs in about 1%. The mortality rate is very low (<0.1%). Systemic complications are not infrequent, particularly with intravenous digital subtraction angiography. The complication rate of cerebral angiography must be considered when evaluating the risks of carotid endarterectomy in patients with ischemic cerebrovascular disease. (Stroke 1990;21:209-222)
“…Unfortunately, this question was not addressed in a subsequent paper. 30 The authors incidentally found no significant difference in side effects between the different contrast media.…”
We review the eight prospective and seven retrospective studies from which it is possible to derive the complication rate of conventional cerebral angiography for patients with mild ischemic cerebrovascular disease who are potential candidates for carotid endarterectomy. Three studies of intravenous and one of intra-arterial digital subtraction angiography are also examined. An overview of the results suggests that the risk of a neurological complication (TIA or stroke) is about 4% and that a permanent neurological deficit (disabling stroke) occurs in about 1%. The mortality rate is very low (<0.1%). Systemic complications are not infrequent, particularly with intravenous digital subtraction angiography. The complication rate of cerebral angiography must be considered when evaluating the risks of carotid endarterectomy in patients with ischemic cerebrovascular disease. (Stroke 1990;21:209-222)
“…Despite advances, cerebral angiography continues to be used for the examination of patients with cerebrovascular diseases. In the past decade, safer contrast agents have been used and there have been important technical advances including smaller catheters, hydrophylic guide wires, and digital imaging systems (5)(6)(7). The purpose of this prospective study was to identify the risk factors for neurologic complications that are related to cerebral angiography.…”
“…Four‐vessel angiographic examination, performed by an experienced neuroradiologist, is usually a straightforward procedure in these patients, but may occasionally be time consuming. Despite improvements of catheters and contrast media, complications to IA‐DSA occur in approximately 1% of the procedures (5, 9). Minimal‐ or non‐invasive methods replacing IA‐DSA could reduce the time before the aneurysm is treated without exposing these patients to the risk of complications to IA‐DSA.…”
CTA in SAH is of great value in demonstrating vascular anatomy and the exact size of an aneurysm. However, IA-DSA is still needed for diagnostic evaluation in aneurysms smaller than 5 mm in diameter, especially in those located near bony structures.
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