Attempts at complete catheterization of the left heart by transseptal and retrograde routes are not always completely informative nor entirely free from complications (Crowley and Parkin, 1956; KavanaghGray and Drake, 1958;Aldridge, 1964;Samet, Bernstein, and Levine, 1965;Christiansen and Wennevold, 1966)
TECHNIQUEThe patient, premedicated with pethidine, lies supine and the apex beat is located by palpation. The site and direction of entry at the apex is determined by screening a forceps tip or needle. This site is anaesthetized down to the pericardium, and after a minute or two, a small skin puncture hole is made with the tip of a scalpel.A 19-gauge needle, 20 cm. (8 in.) long, over which an 18-gauge teflon catheter fits snugly, is connected by a length of tubing to the pressure transducer. The catheter with needle trocar is now advanced through the skin and subcutaneous tissues, pointing in the long axis of the heart towards the second right chondrosternal junction until the tip is seen and felt to touch the apex of the heart. It is then inserted rapidly through the ventricular wall, entry into the left ventricle being confirmed immediately by the appearance of a left ventricular pressure tracing on No. 6 or 7 Gensini catheter is passed into the heart. When the catheter tip is placed satisfactorily in the appropriate chamber, angiocardiography is carried out in the usual way. If attempted catheterization of the left atrium has been unsuccessful, a further attempt can be made using the stiffer catheter. In the earliest patients studied, the catheter was stitched to the chest wall, since Levy and Lillehei had noted recoil of the catheter at the time of pressure injection, but later we found this to be unnecessary with the Gensini catheter.After the procedures have been completed the catheter is removed from the heart and pressure maintained over the puncture for two or three minutes. The whole undertaking usually takes about 20 to 30 minutes, but if no angiography is required, pressure records may be obtained in a matter of 10 to 15 minutes.
SUBJECTSStudies were made on 22 dogs in an attempt to evaluate the method. Special interest was taken in the amount of bleeding into the pericardium and pleura, ease of entry into the desired areas, damage to the lung, and the incidence of serious arrhythmias.Eighteen dogs were divided into three groups of six.The first group had one clean ventricular puncture and the full procedure carried out using a No. 6 Gensini catheter as described above. The second group had three cardiac punctures and then the full procedure carried out once using a No. 6 Gensini catheter, since it was felt that the effect of several attempts at this procedure should be known. The third group had one cardiac 402