Complications Associated with Distraction Osteogenesis

Stucki-McCormick, Suzanne U.; Clarizio, Louis F.

doi:10.1007/978-3-030-40150-4_3

Cited by 3 publications

(2 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…(2014) [ 20 ] Restoring length after digital amputations and relatively technically easy with no donor-site morbidity Long duration of treatment and high complication rates Suzanne et al. (2020) [ 25 ] The application of force over time for the generation of all tissues: skin, muscle, nerves, blood vessels and bone Force-related complications including misshaped regenerate, tipping of the regenerate and open bite Dogra et al. (2020) [ 26 ] Correcting the gross mandibular asymmetry Scar formation and requirement of frequent patient follow up …”

Section: The Advantages and Disadvantages Of Do In Bone Regenerationmentioning

confidence: 99%

Overview of methods for enhancing bone regeneration in distraction osteogenesis: Potential roles of biometals

Pan

et al. 2021

Journal of Orthopaedic Translation

View full text Add to dashboard Cite

Background Distraction osteogenesis (DO) is a functional tissue engineering approach that applies gradual mechanical traction on the bone tissues after osteotomy to stimulate bone regeneration. However, DO still has disadvantages that limit its clinical use, including long treatment duration Methods Review the current methods of promoting bone formation and consolidation in DO with particular interest on biometal. Results Numerous approaches, including physical therapy, gene therapy, growth factor-based therapy, stem-cell-based therapy, and improved distraction devices, have been explored to reduce the DO treatment duration with some success. Nevertheless, no approach to date is widely accepted in clinical practice due to various reasons, such as high expense, short biologic half-life, and lack of effective delivery methods. Biometals, including calcium (Ca), magnesium (Mg), zinc (Zn), copper (Cu), manganese (Mn), and cobalt (Co) have attracted attention in bone regeneration attributed to their biodegradability and bioactive components released during in vivo degradation. Conclusion This review summarizes the current therapies accelerating bone formation in DO and the beneficial role of biometals in bone regeneration, particularly focusing on the use of biometal Mg and its alloy in promoting bone formation in DO. Translational potential: The potential clinical applications using Mg-based devices to accelerate DO are promising. Mg stimulates expression of multiple intrinsic biological factors and the development of Mg as an implantable component in DO may be used to argument bone formation and consolidation in DO.

show abstract

Section: The Advantages and Disadvantages Of Do In Bone Regenerationmentioning

confidence: 99%

Overview of methods for enhancing bone regeneration in distraction osteogenesis: Potential roles of biometals

Pan

et al. 2021

Journal of Orthopaedic Translation

View full text Add to dashboard Cite

show abstract

“…Also, as the desired advancements can be visualized, the length of distraction and vector planning can be easily carried out avoiding further complications due to unwanted interferences. 20 A prospective study done by Chen et al 21…”

Section: Role Of Vsp In Planning Domentioning

confidence: 99%

Complications of distraction osteogenesis: Narrative review

et al. 2021

View full text Add to dashboard Cite

The aim of this narrative review is to discuss the complications of distraction osteogenesis (DO) of facial skeleton and their management. Materials and Method:A detailed literature search was done on PubMed, Google Scholar and Embase from the year 1990 onwards. Any systematic review, randomized controlled trial, controlled clinical trial, retrospective/prospective study discussing about complications of maxillofacial DO and their management were included.Results: Complications related to DO were divided based on phases as (a) planning (patient counselling, improper vector, errors in device selection, etc.), (b) surgery (tooth injury, neurosensory disturbance, incomplete osteotomy, etc.), (c) distraction (device failure, pain at regenerate site, premature consolidation, etc.) and (d) consolidation (infection, hypertrophic scar, relapse, etc.). Conclusion:Widespread applications are possible with DO though it is a devicedependent and technique-sensitive procedure. With proper planning and execution, DO can become the gold standard for managing various maxillofacial disorders.

show abstract

Craniofacial Tissue Regeneration Through Distraction Osteogenesis

Kerkfeld,

Meyer

2023

Fundamentals of Craniofacial Malformations

View full text Add to dashboard Cite

Complications Associated with Distraction Osteogenesis

Cited by 3 publications

References 36 publications

Overview of methods for enhancing bone regeneration in distraction osteogenesis: Potential roles of biometals

Overview of methods for enhancing bone regeneration in distraction osteogenesis: Potential roles of biometals

Complications of distraction osteogenesis: Narrative review

Craniofacial Tissue Regeneration Through Distraction Osteogenesis

Contact Info

Product

Resources

About