Complication Rates After Total Hip and Knee Arthroplasty in Patients With Hepatitis C Compared With Matched Control Patients

Abstract

Further research is needed to establish quantifiable associations between hepatitis C and postoperative complications among patients with the disease who undergo total joint arthroplasty.

Does pre-arthroplasty antiviral treatment for hepatitis C reduce complication rates after total shoulder arthroplasty? A matched cohort study

“…HCV has been previously recognized as a risk factor for prosthesis-related complications following elective arthroplasty. 18 Prior research has associated HCV infection with a greater risk of PJI, 11 , 31 mechanical complications, 8 , 38 and revision surgery 23 , 31 after both total knee arthroplasty and total hip arthroplasty. At 1- and 2 years postoperatively, HCV patients in this study exhibited significantly higher rates of revision TSA, PJI, dislocation, and other mechanical complications compared to matched controls.…”

What’s New in Hip Replacement

“…There are mixed reports regarding the outcomes of THA among patients with hepatitis C. In a mid-term follow-up study, patients with hepatitis C were found to have similarly good implant survivorship and clinical outcomes after THA compared with matched controls 31 . Cancienne et al, however, showed that patients with hepatitis C had significantly higher risk of infection, aseptic revision surgery, medical complications, and blood transfusions compared with a matched cohort followed for up to 8 years 32 .…”

Total Joint Arthroplasty Should Not Be Delayed in Hepatitis C Patients After Successful Treatment Achieving a Sustained Viral Load

“…Consequently, a study conducted by Cancienne et al. determined that HCV patients who did not receive treatment prior to total knee arthroplasty had higher rates of both infection and aseptic revision 3 months following surgery, which renewed interest in optimizing this high-risk cohort prior to TJA [ 13 ].…”