school of medicine and Palo Alto VA Health Care System Introduction:The cost of medications in the treatment of hypertension and diabetes in the morbidly obese is a significant healthcare burden. In this study we assessed the impact of gastric bypass surgery on medication costs over the course of a lifetime.
Methods:We performed a retrospective chart review of patients who had gastric bypass at the Palo Alto VA Health Care System from 2001 to 2007. Preoperative and postoperative medications to treat hypertension and diabetes were identified. Life expectancy was determined using CDC life expectancy tables and Framingham Heart Study data based on body mass index. Comparisons were made between the projected lifetime costs of diabetic and hypertensive medications with or without bariatric surgery using the Student's paired t-test.Results: Of 106 patients who had gastric bypass, 90 had either hypertension or diabetes. Of these patients, 88 (83%) had hypertension and 60 (57%) had diabetes before surgery. Hypertension resolved in 44% and diabetes in 80% at one year after surgery. The projected average lifetime cost of medications to treat hypertension without and with gastric bypass surgery was $1,038.31 vs. $285.98 (p< 0.0001), respectively. To treat diabetes the difference was $10,504.86 vs. $1,139.46 (p< 0.0001) per person. When the subset of patients whose hypertension and diabetes had completely resolved was excluded, the projected average lifetime cost of hypertensive medications without and with gastric bypass was $1,348.57 vs. $513.69 (p< 0.0006), respectively. The projected average lifetime cost of diabetic medications without and with surgery was $22,427.34 vs. $5,697.31 (p< 0.026) respectively.
Conclusion:Gastric bypass surgery results in a significant reduction in the lifetime cost of medications to treat hypertension and diabetes in the morbidly obese. These cost-savings are also significant in the subset of patients without complete resolution of their comorbid conditions after surgery.Objective: High-risk patients are at significant risk for venous thromboembolism (VTE) and may benefit from the addition of retrievable inferior vena cava filters (rIVCF) to chemoprophylaxis. However, the optimal VTE prophylaxis has not been established in morbidly obese patients undergoing bariatric surgery. This observational study examines the use of rIVCFs in combination with chemoprophylaxis for high-risk bariatric surgery patients.Methods: A retrospective review was performed of all high-risk morbidly obese patients who underwent bariatric surgery between February 2007 and July 2009. Patients were considered high-risk for the development of a peri-operative VTE if they had a prior history of VTE, a BMI 55 kg/m2, were severely immobile, or had preexisting hypercoaguable condition. All patients underwent a preoperative venous duplex study. RIVCF placement was performed preoperatively on the day of the bariatric procedure. Standard chemoprophylaxis was initiated preoperatively and continued throughout the hospital stay. C...