Complicated rheumatoid disease.

Hart, F. Dudley

doi:10.1136/bmj.2.5506.131

Cited by 19 publications

(4 citation statements)

References 24 publications

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“…Our patient had a long‐standing history of rheumatoid arthritis. According to previous reports, the appearance of cutaneous necrotizing palisading granulomas in the context of rheumatoid arthritis indicates a more severe prognosis and the course tends to be more aggressive 3,4 …”

Section: Discussionmentioning

confidence: 94%

Cutaneous palisaded allergic granuloma associated with rheumatic disease

Hamacher

Gibson

2002

Int J Dermatol

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A 62-year-old man presented with a 5-year history of symmetric, hard papules on both of his elbows. These lesions were completely asymptomatic, but they were of cosmetic concern to the patient. Summer and trauma reportedly exacerbated the appearance of new papules, which tended to evolve spontaneously, harden, and subsequently ulcerate. The patient's main medical problem was a long-standing history of rheumatoid arthritis treated with low-dose oral prednisone. Physical examination revealed multiple scattered papules bilaterally on the extensor surfaces of the forearms. These were 2-10 mm in size, red to violaceous, and hard. Some of the lesions had ulcerated centers or slight umbilication (Fig. 1A,B). Histologic examination revealed several granulomas in the mid- to deep dermis with central basophilic fibrillar collagen necrosis (Fig. 2A). The necrotic areas were interspersed with bands of neutrophils, lymphocytes, and leukocytoclastic debris. The periphery of these basophilic granulomas was lined by palisading histiocytes (Fig. 2B).

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Section: Discussionmentioning

confidence: 94%

Cutaneous palisaded allergic granuloma associated with rheumatic disease

Hamacher

Gibson

2002

Int J Dermatol

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“…Inflammatory arteritis per se may complicate rheumatoid arthritis at any time, usually affecting patients with severe arthritis, subcutaneous nodules, and high titres of rheumatoid factor (Bywaters and Scott, 1963). This necrotizing arteritis is indistinguishable histologically from polyarteritis nodosa and may similarly cause a wide variety of clinical manifestations having a grave prognosis (Hart, 1966), differing from the latter, however, in that peripheral sensorimotor neuropathy is the most frequent manifestation in rheumatoid arthritics (Palis and Scott, 1965).…”

Section: Commentmentioning

confidence: 99%

“…Acute Abdomen in Rheumatoid Arthritis due to Necrotizing Arteritis M. K. LINDSAY, H. B. TAVADIA, A. S. WHYTE, P. LEE, J. WEBB British Medical Journal, 1973, 2, 592-593 Though the major features of rheumatoid arthritis are related to the joint morbidity a wide variety of systemic manifestations may occur at any time as specific complications of "malignant" rheumatoid disease (Hart, 1966). The most serious of these complications are due to necrotizing arteritis.…”

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confidence: 99%

Acute abdomen in rheumatoid arthritis due to necrotizing arteritis.

Lindsay¹,

Tavadia²,

Whyte³

et al. 1973

BMJ

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“…The larynx is a part of upper respiratory system and an aerodigestive crossroads and is, therefore, often affected by pathological changes specific for rheumatoid arthritis. Damage of its anatomical structures and physiological functions happens in the early phases of rheumatoid arthritis, as many authors have written about it (Hart, 1966), which is manifested by different pathoanatomical and pathophysiological changes. Sequence and intensity of the symptoms' appearance depend on the size, localization, spread and duration of pathological changes in rheumatoid arthritis.…”

Section: Introductionmentioning

confidence: 99%