Compliance with malaria chemoprophylaxis and preventative measures against mosquito bites among Dutch travellers.

Cobelens, Frank; Leentvaar-Kuijpers, A

doi:10.1046/j.1365-3156.1997.d01-357.x

Cited by 39 publications

(37 citation statements)

References 13 publications

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“…Whereas previous studies showed no association [28] or even a competition [35] between the use of prophylactic measures, the present study showed that those who stated compliance with chemoprophylaxis also stated compliance with anti-mosquito measures, suggesting common determinants of these prophylactic behaviors.…”

Section: Discussioncontrasting

confidence: 94%

Determinants of compliance with malaria chemoprophylaxis among French soldiers during missions in inter-tropical Africa

Resseguier

Machault

Ollivier

et al. 2010

Malar J

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BackgroundThe effectiveness of malaria chemoprophylaxis is limited by the lack of compliance whose determinants are not well known.MethodsThe compliance with malaria chemoprophylaxis has been estimated and analysed by validated questionnaires administered before and after the short-term missions (about four months) in five tropical African countries of 2,093 French soldiers from 19 military companies involved in a prospective cohort study. "Correct compliance" was defined as "no missed doses" of daily drug intake during the entire mission and was analysed using multiple mixed-effect logistic regression model.ResultsThe averaged prevalence rate of correct compliance was 46.2%, ranging from 9.6%to 76.6% according to the companies. Incorrect compliance was significantly associated with eveningness (p = 0.028), a medical history of clinical malaria (p < 0.001) and a perceived mosquito attractiveness inferior or superior to the others (p < 0.007). Correct compliance was significantly associated with the systematic use of protective measures against mosquito bites (p < 0.001), the type of military operations (combat vs. training activities, p < 0.001) and other individual factors (p < 0.05).ConclusionsThe identification of circumstances and profiles of persons at higher risk of lack of compliance would pave the way to specifically targeted strategies aimed to improve compliance with malaria chemoprophylaxis and, therefore, its effectiveness.

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Section: Discussioncontrasting

confidence: 94%

Determinants of compliance with malaria chemoprophylaxis among French soldiers during missions in inter-tropical Africa

Resseguier

Machault

Ollivier

et al. 2010

Malar J

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“…In agreement with several previou s studies, many of our CFS patients appeared to have several complaints suggestive of autonomic dysfunction such as increased sweating, dysphagia, and constipation [9,20]. Nevertheless, extensive cardiovascular reflex testing did not disclose definite autonomic dysfunction in this unselected group of CFS patients.…”

Section: Discussionsupporting

confidence: 91%

Autonomic function in patients with chronic fatigue syndrome

Soetekouw

Lenders

Bleijenberg

et al. 1999

Clinical Autonomic Research

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Subtle signs of autonomic dysfunction and orthostatic intolerance have been reported in patients with chronic fatigue syndrome (CFS). To assess cardiovascular autonomic function noninvasively in an unselected group of patients with CFS, we examined responsiveness to several cardiovascular reflex tests in 37 CFS patients and 38 healthy control subjects. Blood pressure and heart rate (HR) were recorded continuously by a Finapres device before and during forced breathing, standing up, Valsalva maneuver, and sustained handgrip exercise (HG). In addition, a mental arithmetic test was carried out and questionnaires to assess the severity of CFS symptoms were completed. At rest, there were no significant differences in blood pressure or in HR between the two groups. The in- and expiratory difference in HR tended to be lower in CFS patients (28.4 +/- 10.5 beats) than in healthy controls (32.2 +/- 9.5) (p = 0.11). The maximal increase in HR during standing up was not significantly different between the CFS group (37.6 +/-8.9 beats) and the control group (40.2 +/- 8.9 beats). There were no significant differences between both groups with regard to the Valsalva ratio, but the systolic and diastolic blood pressure responses were significantly larger in CFS patients, despite the fact that many CFS patients were not able to sustain the Valsalva maneuver. The HR response to MA was significantly less in the CFS group (22.6 +/- 9.9) than in the control group (29.5 +/- 16.7) (p < 0.05), suggesting impaired cardiac sympathetic responsiveness to mental stress. The lower HR responses could not be explained by the level of concentration in the CFS group. During HG exercise, the hemodynamic responses were lower in the CFS group than in the control group, but this might be attributed to the lower level of muscle exertion in CFS patients. There were no significant differences between CFS patients with and without symptoms of autonomic dysfunction regarding the hemodynamic responses to the cardiovascular reflex tests. The findings of the study suggest that there are no gross alterations in cardiovascular autonomic function in patients with CFS.

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“…Pesticides that are volatile enough to diffuse through air negate the need to treat the skin or clothing and can protect a space surrounding a delivery point so that a single unit can protect multiple users for long periods [15] without requiring regular re-application or unrealistic levels of user compliance [33]. …”

Section: Discussionmentioning

confidence: 99%

Target product profiles for protecting against outdoor malaria transmission

Killeen

Moore

2012

Malar J

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BackgroundLong-lasting insecticidal nets (LLINs) and indoor residual sprays (IRS) have decimated malaria transmission by killing indoor-feeding mosquitoes. However, complete elimination of malaria transmission with these proven methods is confounded by vectors that evade pesticide contact by feeding outdoors.MethodsFor any assumed level of indoor coverage and personal protective efficacy with insecticidal products, process-explicit malaria transmission models suggest that insecticides that repel mosquitoes will achieve less impact upon transmission than those that kill them outright. Here such models are extended to explore how outdoor use of products containing either contact toxins or spatial repellents might augment or attenuate impact of high indoor coverage of LLINs relying primarily upon contact toxicity.ResultsLLIN impact could be dramatically enhanced by high coverage with spatial repellents conferring near-complete personal protection, but only if combined indoor use of both measures can be avoided where vectors persist that prefer feeding indoors upon humans. While very high levels of coverage and efficacy will be required for spatial repellents to substantially augment the impact of LLINs or IRS, these ambitious targets may well be at least as practically achievable as the lower requirements for equivalent impact using contact insecticides.ConclusionsVapour-phase repellents may be more acceptable, practical and effective than contact insecticides for preventing outdoor malaria transmission because they need not be applied to skin or clothing and may protect multiple occupants of spaces outside of treatable structures such as nets or houses.

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Compliance with malaria chemoprophylaxis and preventative measures against mosquito bites among Dutch travellers.

Cited by 39 publications

References 13 publications

Determinants of compliance with malaria chemoprophylaxis among French soldiers during missions in inter-tropical Africa

Determinants of compliance with malaria chemoprophylaxis among French soldiers during missions in inter-tropical Africa

Autonomic function in patients with chronic fatigue syndrome

Target product profiles for protecting against outdoor malaria transmission

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