Compliance with iron and folic acid supplementation and associated factors among pregnant women in Ethiopia: a systematic review and meta-analysis

Abstract

<p><strong>Background:</strong> Anaemia is one of the world’s leading cause of disability and the most serious global health issues. Globally about 38% (32 million) pregnant women are anaemic, from which 46.3% (9.2 million) are in Africa.</p><p><strong>Methods:</strong> Works of articles from PubMed, Medline and Google Scholar journal data-base were considered. Entirely articles allied to compliance and determinants of AFA supplementation were captured. The authors used modified Newcastle-Ottawa quality appraisal rule for cross-sectional works to assess the excellence of the studies for consideration and, tracked preferred reporting items for systematic reviews and meta-analysis guideline. The pooled effect size was calculated with the review manager and compressive meta-analysis software.</p><p><strong>Results:</strong> Eighteen studies with a total of 6649 pregnant women were included for analysis. Compliance of IFA supplementation in pregnancy in Ethiopia was 46.1%. Women who had experienced counselling on IFAS were 1.16 times, OR:1.16, (95% CI, 0.54, 2.50), knowledge on IFAS were 3.20 times, OR:3.20, (95% CI, 1.31, 7.85), knowledge of anaemia were five times OR:5.10, (95% CI, 1.87, 13.94), fourth visit for ANC were 1.58 times OR:1.58, (95% CI, 0.59, 3.42) and early registration for ANC were three times OR: 3.19, (95% CI, 0.77, 13.26) more likely to have compliance with IFAS compared to their counterpart.</p><p><strong>Conclusions</strong>: There is low compliance of IFAS in different parts of Ethiopia. Lack of counselling on IFAS, knowledge of IFAS and anaemia, no fourth visit for ANC and timing in ANC registration were factors that hinder compliance of IFAS.</p>

Utilization and compliance with iron supplementation and predictors among pregnant women in Southeast Ethiopia

“…The present study supported a study conducted in four regions of Ethiopia 20 . Likewise, the current study findings agreed with several studies carried out in Northwest Ethiopia 50 , Aykal Town 30 , North Wollo Zone 53 , and Ethiopia 60 , 61 . The probable reason could be the awareness and educational status of the respondents.…”

“…Pregnant women who had good knowledge of iron supplementation were 3.30 times more likely to be compliant with iron supplements as compared to pregnant women who had poor knowledge of iron supplementation. This current study was agreed with several studies carried out in Burji District 49 , West Dembia, Ethiopia 50 , Aykal town 30 , North Wollo zone 53 , Debre Tabor 52 , Debre Markos town 56 , Ethiopia 60 , 61 . Likewise, the current study supported studies conducted in SSA 63 , Kenya 65 , Nigeria 24 , Muntinlupa, and the Philippines 79 .…”

Determinants of non-adherence to Iron Folic Acid Supplementation among Pregnant Women Attending Public Health Facilities in Bishoftu Town, Ethiopia: Case-Control study

“…Pregnant women who started their rst ANC at greater than 16 weeks were 2.4 times more likely to non-Adherence to IFAS than their counterparts. This nding is in line with the study done in Central Ethiopia (43), Lay Armachiho Northwest Ethiopia (37), and at Hosanna Town of Southern Ethiopia (18). A study done at Tikur Anbessa specialized hospital showed that Gestational age at the rst ANC visit was signi cantly associated with adherence to IFAS.…”

Counseling intervention on iron-folic acid adherence and clinical outcomes among pregnant women and women planning to be pregnant: a scoping review

“…According to WHO Adherence to Therapies: evidence for action, 19 adherence includes a wide range of behaviors related to health that go beyond taking prescribed medications. WHO also agrees to call adherence "the extent to which the patient follows medical instructions".…”

“…Providing counseling to pregnant women to improve adherence to taking blood-added supplements has resulted in significant benefits and impacts on changes in adherence of pregnant women in several studies that have been conducted in several countries. [17][18][19][20][21] Based on the background explained above, the researcher wants to undertake additional research on the subject of counseling intervention's impact on increasing adherence among pregnant women and those women planning to be pregnant, to determine whether counseling has this effect through literature studies.…”