Recently, despite the development of cancer pain treatment, many cancer patients still suffer from pain. This review aimed to explore the patients-related barriers to pain management among cancer patients. The electronic searching was conducted in a different database: Google Scholar, CINAHL and PubMed. According to previous studies barriers can classified into patients/family-related barriers, health care provided-related barriers, and institutional-related barriers. Patient-related barriers were reluctant to report pain, fear from tolerance, addiction, and side effect, and culture. This review provides summary data about the patient-barriers to effective cancer pain control.