Complexation of the antibiotic tetracycline with humic acid

Gu, Cheng; Karthikeyan, K. G.; Sibley, Samuel D.; Pedersen, Joel A.

doi:10.1016/j.chemosphere.2006.08.028

Cited by 334 publications

(168 citation statements)

References 44 publications

Supporting

Mentioning

151

Contrasting

Unclassified

Order By: Relevance

“…Further, another study suggests a large portion of the drug passes unabsorbed through the intestine of fish and reaches the environment where most of the drug (99.9%) was recovered from the water and sediment in a concrete pond after medication of eels by feeding 37) . Therefore, a substantial amount of OTC id deposited in the sediment as this is the possible fate of OTC administred to cultured fish; however, the bioavailability of OTC in the sediment may be reduced by the interaction of OTC with multivalent cations 21) or humic acid 15) . The large amount of OTC in fish feces 27) suggests that the fish intestines play an important role in the selection of resistant bacteria.…”

Section: Discussionmentioning

confidence: 99%

Distribution of Tetracycline Resistance Gene, tet(M), in Gram-Positive and Gram-Negative Bacteria Isolated from Sediment and Seawater at a Coastal Aquaculture Site in Japan

2007

View full text Add to dashboard Cite

We found increased numbers of oxytetracycline (OTC)-resistant bacteria in sediment and seawater around a marine aquaculture site after OTC therapy. Samples were collected at an aquaculture site along the coast of the Seto Inland Sea, Japan in 2004. In April, the percentage of bacteria resistant to 60 µg mL −1 OTC in the surface sediment was 6.8%-20.0%. The percentages increased during OTC therapy in the summer reaching 53.3%-60.7% in September. Ninety-two days after drug cessation, the percentages decreased to below 22.9%. Tet(M)-positive bacteria were detected in the sediment and seawater samples. Tet(M) was evident in both Gram-positive and Gram-negative bacteria from various genera, and was newly identified in Paenibacillus, Sporosarcina, Shewanella, and Pseudoalteromonas. The dominant tet(M)-positive isolates were strains of Vibrio suggesting that this genus is an important reservoir for tet(M) in the marine environment. Two different alleles were found, tet(M)-A and tet(M)-B, each in isolates from five genera. The data suggests drug therapy used in the aquaculture acted as a selective pressure promoting increased numbers of resistant bacteria.

show abstract

Section: Discussionmentioning

confidence: 99%

Distribution of Tetracycline Resistance Gene, tet(M), in Gram-Positive and Gram-Negative Bacteria Isolated from Sediment and Seawater at a Coastal Aquaculture Site in Japan

2007

View full text Add to dashboard Cite

show abstract

“…Thus, their extensive use and frequent application of animal manures as plant nutrients and soil amendments resulted in accumulation in soils and aquatic systems. For these reasons, many studies were conducted on their interactions with soils, iron oxides, and other clay minerals over the last 10 years (Figueroa et al 2004(Figueroa et al , 2010Figueroa and Mackay 2005;Karthikeyan 2005, 2008;Gu et al 2007;Chang et al 2009aChang et al , b, 2012Li et al 2010a, b). Although the removal of TC from water was via adsorption onto many types of the geologic solids, degradation of TC in the presence of manganese oxide was also attributed to one of the major mechanisms of TC removal (Chen and Huang 2011;.…”

Section: Introductionmentioning

confidence: 99%

Sorption and desorption of tetracycline on layered manganese dioxide birnessite

Jiang

Chang

Wang

et al. 2014

Int. J. Environ. Sci. Technol.

View full text Add to dashboard Cite

Birnessite is one of the most common manganese oxides in the clay-sized fraction (\2 lm) of soils and has high cation exchange capacity and larger surface area. Birnessite was previously studied for decomposition of selected antibiotics from water. In this study, the removal of tetracycline (TC) by birnessite from aqueous solution was investigated as a function of initial tetracycline concentration, solution pH, temperature, and equilibrium time. Changes in solid phase after TC adsorption and desorption were characterized by X-ray photoelectron spectroscopy, X-ray diffraction (XRD), and Fourier transform infrared analyses. Desorption of exchangeable cations accompanying TC removal and partial desorption of TC from birnessite by AlCl 3 confirmed that cation exchange was responsible for TC removal at low initial concentrations. Both the external and internal surface areas were readily available for TC uptake by birnessite. The intercalated TC formed a horizontal monolayer configuration in the interlayer of birnessite as deduced from XRD analyses.

show abstract

“…However, the positively charged -NH(CH 3 ) 2 functional group could interact with adsorption sites of negatively charged clay minerals through electrostatic interaction, or cation exchange with those previously attached to mineral surfaces (Figueroa et al 2004). In addition, TC could adsorb to the surfaces of metal oxides via surface complexation of metal ions (Gu et al 2007). TC contains multiple polar functional groups and could form hydrogen bonding with the polar part of soils (Gu et al 2007).…”

Section: Introductionmentioning

confidence: 99%

Desorption of tetracycline from montmorillonite by aluminum, calcium, and sodium: an indication of intercalation stability

Chang

Jean

et al. 2013

Int. J. Environ. Sci. Technol.

View full text Add to dashboard Cite

As the uptake of cationic drugs, such as tetracycline (TC), was attributed to cation exchange, the stability of adsorbed TC on a Ca-montmorillonite SAz-2 was studied using cationic solutions of different valence charges under different pH conditions. At the initial loading of 356 mg g -1 , the amounts of TC desorbed by 0.05 M AlCl 3 , CaCl 2 , and NaCl were 133 ± 4, 83 ± 6, and 50 ± 4 mg g -1 , respectively, or 37, 23, and 14 %. However, when the amount or percentage of TC desorbed was normalized to the equivalence of each cation, the values were in the range of 44-50 mg g -1 or 11-14 % per 10 mmol of charge. The kinetics of TC desorption were moderately fast and almost reached equilibrium in 6 h. The results followed the pseudo-second-order kinetic model with reaction rate in the order of AlCl 3 [ CaCl 2 [ NaCl at a higher initial TC loading level. The total amount of TC desorbed after five desorption cycles followed the order of AlCl 3 [ CaCl 2 [ NaCl, too, suggesting that cations with higher positive charges, thus, less hydrated, are preferred to remove adsorbed cationic drugs. The FTIR analyses showed larger band shift when Al 3? was used as the desorbing reagent. The XRD patterns before and after TC desorption revealed no changes in basal spacing, even after five desorption cycles, suggesting that the removal of TC from SAz-2 was largely from the external surfaces.

show abstract

Complexation of the antibiotic tetracycline with humic acid

Cited by 334 publications

References 44 publications

Distribution of Tetracycline Resistance Gene, tet(M), in Gram-Positive and Gram-Negative Bacteria Isolated from Sediment and Seawater at a Coastal Aquaculture Site in Japan

Distribution of Tetracycline Resistance Gene, tet(M), in Gram-Positive and Gram-Negative Bacteria Isolated from Sediment and Seawater at a Coastal Aquaculture Site in Japan

Sorption and desorption of tetracycline on layered manganese dioxide birnessite

Desorption of tetracycline from montmorillonite by aluminum, calcium, and sodium: an indication of intercalation stability

Contact Info

Product

Resources

About