“…have reported the complexation and/or chiral recognition thermodynamics of aminated β -CDs possessing a positive charge with neutral/charged guests, respectively, revealing the counterbalance between electrostatic and conventional intracavity interactions. We have investigated the complexation thermodynamics of a series of modified CDs carrying different substituent groups, such as pyridinio, phosphonyl, anilineo, arylseleno, furfuryl, and quinolyl, with guests l -tryptophan, naphthalene derivatives, aliphatic alcohols and so on, with results that indicate electronic effect, the original conformation of modification group-tethered β -CDs, and the size/shape-fitted relationship between the host cavity and the guest diameter directly influence the binding ability. − However, the thermodynamic behavior of CD derivatives linked by a rigid aromatic ring has scarcely been reported thus far, although these investigations are very important in understanding the structure-energetics correlation in molecular recognition. In this respect, some representative molecules, such as homologous cycloalkanols, borneol, and camphor, were selected as guests to measure their binding ability with CD derivatives.…”