Complexation of Furosemide with Fulvic Acid Extracted from Shilajit: A Novel Approach

Synthesis and characterization of furosemide‐loaded sericin/alginate beads subjected to thermal or chemical cross‐linking for delayed and sustained release

“…Stretching of benzene's CO and CC bonds are related to 1670 and 1560 cm −1 bands, respectively. Bands related to the angular deformation of NH bond at 1672 cm −1 and the asymmetric elongation of SO groups at 1260 cm −1 are also present 47,48 . The presence of furosemide characteristics bands in the spectra of the formulations confirms its incorporation in its original form, as previously evidenced by XRD analysis.…”

Part V—sorption of pharmaceuticals and personal care products

“…Nonlinear sorption and sorption-desorption hysteresis between tetracycline and DOM have been recently observed (Gu et al 2007), which could be valuable evidence to attract research interest on nonideal PPCP-DOM interactions. Also, because of the presence of functional groups, various species, and metabolites, PPCPs could bind with DOM in a more complicated way compared to HOCs, such as amorphous inclusion complex (Agarwal et al 2008). Because the same methods as for HOC-DOM studies are employed for investigating PPCP-DOM interactions, such as fluorescence (Yamamoto et al 2003), equilibrium dialysis (Gu et al 2007;Yamamoto et al 2004), solubility enhancement (Yamamoto et al 2003), and cross-flow ultrafiltration , the limitations of those methods are the same as presented in part IV of this review series.…”

Influence of fulvic acid and hydroxy propyl-β-cyclodextrin on aspirin degradation

“…The FA obtained in 0.1 N NaOH was passed through hydrogensaturated cation exchange resin to exchange the sodium ions with hydrogen ions. The final FA solution was concentrated and freeze dried to obtain amorphous FA 11,14 . Complexes of ASA with FA and hydroxypropyl-βcyclodextrin were prepared using different techniques such as solvent evaporation, freeze drying, and spray drying in the molar ratios 1:0.5, 1:1, and 1:2 (ASA:FA/HP-β-CD).…”

“…FAs are the major constituent of shilajit, having relatively open, flexible structure punctured by voids (micropores) of different diameters 9,10 . These compounds were, presumably, loosely held in the core Complexation of aspirin with fulvic acid and HP-b-CD structure of Shilajit 11 . The plant's secondary metabolites that are trapped in the internal voids of FAs are spared from and become resistant to common chemical and biological decomposition 12 .…”