Complexation of Achiral Calixarenes with Chiral Pharmaceutical Substances: A Circular Dichroism Study

The Influence of Lipid Matrix Composition on the Microenvironment of Levofloxacin in Liposomal Forms

“…In the CD spectrum of LF, the most informative region is in the range of 220–310 nm with characteristic ellipticity maxima or minima [ 20 ]. In order to analyze the changes in the CD spectra when LF is included in a lipid bilayer, it is necessary to trace in independent experiments how the LF spectrum changes when the ionic state changes.…”

Biomedical Applications of Supramolecular Systems Based on Host–Guest Interactions

“…Furthermore, circular dichroism was used to study the inclusion mechanism between achiral CAs and chiral pharmaceutical reagents in different solvents, such as acetonitrile, methanol, and water. The obtained results suggested that CAs could act as ideal hosts to encapsulate various unit by both upper and lower rims . By employing the spectrometry and 1 H NMR techniques, it was found that the inclusion between p -sulfonatocalix­[6]­arene and vitamin B6 was mainly driven by hydrophobic and hydrogen-bonding interactions assisted by electrostatic interaction.…”

“…The obtained results suggested that CAs could act as ideal hosts to encapsulate various unit by both upper and lower rims. 176 By employing the spectrometry and 1 H NMR techniques, it was found that the inclusion between psulfonatocalix [6]arene and vitamin B6 was mainly driven by hydrophobic and hydrogen-bonding interactions assisted by electrostatic interaction. Such research provides useful information for future design of macrocyclic molecules in the drug delivery application.…”

Encapsulation of Drug Molecules into Calix[n]arene Nanobaskets. Role of Aminocalix[n]arenes in Biopharmaceutical Field

“…Recent publication, which is devoted to study of eleven drugs with regard to their complexation by CAs 120–121 , 123 , 125–126 , and 142–147 in acetonitrile, methanol, and water, can be also found …”