“…The different ability of cytokines to release PGs in several days of gestation may arise from diverse expression of receptors for particular cytokines in myometrium during pregnancy. To our knowledge, there are only data showing the expression of receptors for IL-1 and IL-8 in human myometrium at term (Hatthachote and Gillespie 1999). As we demonstrated here, cytokines used individually (at a dose of 1 and/or 10 ng/ml) increased more often the output of PGE 2 compared to PGF 2α from myometrial tissues.…”