2023
DOI: 10.3233/jifs-223656
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Complex graph neural networks for medication interaction verification

Abstract: This paper presents the development and application of graph neural networks to verify drug interactions, consisting of drug-protein networks. For this, the DrugBank databases were used, creating four complex networks of interactions: target proteins, transport proteins, carrier proteins, and enzymes. The Louvain and Girvan-Newman community detection algorithms were used to establish communities and validate the interactions between them. Positive results were obtained when checking the interactions of two set… Show more

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Cited by 7 publications
(3 citation statements)
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References 45 publications
(28 reference statements)
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“…Leveraging artificial intelligence (AI) techniques emerges as an enticing approach to addressing this issue. AI, a domain within computer science, demonstrates the capacity to comprehend tasks [134]; analyze data [135]; evaluate time series [136], optimization design [137], and classification tasks [138][139][140]; and make decisions using algorithms crafted by experts [141].…”
Section: Artificial Intelligence Applicationsmentioning
confidence: 99%
“…Leveraging artificial intelligence (AI) techniques emerges as an enticing approach to addressing this issue. AI, a domain within computer science, demonstrates the capacity to comprehend tasks [134]; analyze data [135]; evaluate time series [136], optimization design [137], and classification tasks [138][139][140]; and make decisions using algorithms crafted by experts [141].…”
Section: Artificial Intelligence Applicationsmentioning
confidence: 99%
“…In addition, the cultural, institutional, and technical aspects can also be added, depending on the complexity and need foreseen, as well as the size of each project [66][67][68]. Nowadays, AI-based models are applied considering their capacity to deal with nonlinear data [69][70][71].…”
Section: Technology and Efficiency Improvementmentioning
confidence: 99%
“…Graphs, defined as a set of nodes (vertices) and a set of links (edges) that connect some of those vertices, constitute a very useful tool to represent networks. The application of graphs has received thorough attention from the scientific community since its application is open to a wide number of research areas, with graph neural networks being a recent hot topic [24,25]. Additionally, graph coloring represents another hot topic in the field of discrete mathematics, attracting the interest of the scientific community from the fields of both engineering and mathematics, due to its theoretical challenges and applications [26].…”
Section: Graphs and Channel Selection In Wi-fimentioning
confidence: 99%