Complex formation between arginine and calcium (II) and magnesium (II)

Abstract

The compositions of solutions containing arginine and calcium (II) or magnesium (II) were studied at 25 C and 1.00 mol dm À 3 NaCl or 1.00 mol dm À 3 NaClO 4 , as ionic media. The complex formation in 1.00 mol dm À 3 NaCl was studied by measuring the electromotive force of a galvanic cell, involving a glass electrode, to obtain the free hydrogen ion concentration. The investigation in 1.00 mol dm À 3 NaClO 4 was carried out by measuring the electromotive force of two galvanic cells. The former involved a glass electrode whereas the latter used a silver electrode.The investigation was performed in a wide range of reagent concentrations so that experimental data could be explained for calcium (II) by assuming the presence of 1 : 1 and 1 : 2 complexes, both in 1.00 mol dm À 3 NaCl and 1.00 mol dm À 3 NaClO 4 . Experimental data obtained for magnesium (II) were explained by assuming only the formation of 1 : 1 complexes. In both cases the values of the stability constants were determined. A comparison between the results obtained in 1.00 mol dm À 3 NaCl and 1.00 mol dm À 3 NaClO 4 was performed. An attempt to explain as the complex formation takes place in solution is proposed.

Selected metabolic, epigenetic, nitration and redox parameters in turkeys fed diets with different levels of arginine and methionine

“…Arg contains a basic guanidino group, and it can form chelate rings with certain elements. However, according to Antonilli et al (2009), Arg does not chelate magnesium (II).…”

Peptide–Mineral Complexes: Understanding Their Chemical Interactions, Bioavailability, and Potential Application in Mitigating Micronutrient Deficiency

“…For example, the hydroxyl group of Ser has a strong binding potential with zinc [51]. The side chain of cationic residues at physiological pH would cause electrostatic repulsion with the metals; however, Arg forms complexes with several divalent metals depending on its protonation constant [54,55]. Schematic diagram indicating steps toward the preparation, purification, and identification of mineral-binding peptides from food proteins.…”

“…For example, the hydroxyl group of Ser has a strong binding potential with zinc [51]. The side chain of cationic residues at physiological pH would cause electrostatic repulsion with the metals; however, Arg forms complexes with several divalent metals depending on its protonation constant [54,55]. * Net charges and molecular weights of peptides were calculated using a peptide property calculator (https://pepcalc.com/).…”

L‐argininato copper(II) complexes in solution exert significant selective anticancer and antimicrobial activities

“…[12a-c] Along these properties, the copper(II) complexes with phen or bpy seem to be a new branch of potential antitumor agents against human colon and breast cancers or nasopharyngeal carcinoma. [12d,e] Moreover, the essential amino acid, (S)-2-amino-5-guanidinopentanoic acid, commonly known as L-arginine (L-Arg) forms stable complexes with metal ions, [13][14][15][16][17][18] which have been examined for their various properties e.g., L-arginine complexes of Pt(II) ions were tested for the formation of noncovalent bonds and electrostatic interactions π-π with nucleotides AMP, GA, GMP, IA. [19] Copper(II) complexes with L-arg present strikingly good biological activity [20] because of structural similarities between L-arginine and two natural antibiotics: netropsin and distamycin.…”

“…Moreover, the essential amino acid, ( S )‐2‐amino‐5‐guanidinopentanoic acid, commonly known as L‐arginine (L‐Arg) forms stable complexes with metal ions, [ 13–18 ] which have been examined for their various properties e.g. , L‐arginine complexes of Pt(II) ions were tested for the formation of noncovalent bonds and electrostatic interactions π‐π with nucleotides AMP, GA, GMP, IA.…”