Complex Febrile Seizures in Children with COVID-19 Infection

Abstract

Coronavirus disease 2019 , first reported in Wuhan, China in 2019, is an infectious disease caused by a novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The incidence rate is lower in children than in adults, but as the number of infected patients has increased recently, the number of pediatric patients has also increased [1,2]. The typical symptoms of COVID-19 include fever, cough, chills, aches, headaches, anorexia, and anosmia [1]. Neurological manifestations can also occur in patients with COVID-19. Several studies have reported neurological manifestations of COVID-19 in children [1][2][3][4]. Panda et al. [4] reviewed these manifestations and reported that 16% of all such patients showed non-specific neurological symptoms, such as headache, myalgia, and fatigue, whereas 1% of them showed specific neurological symptoms, such as seizures and encephalopathy. Another study reported that neurological manifestations, including febrile and non-febrile seizures, were observed in 3% of children with COVID-19 [1].Febrile seizures are relatively common neurologic disorders, affecting 2% to 5% of children under the age of 5 years. There are two types of febrile seizures: simple and complex seizures. Simple febrile seizures refer to generalized seizures

Neurological Manifestations of Acute SARS-CoV-2 Infection in Pediatric Patients: A 3-Year Study on Differences between Pandemic Waves

“…This study, as well as others [ 64 , 73 ], discovered that febrile seizures were the most common neurological manifestation among pediatric patients diagnosed with COVID-19. It is worth noting that Kim et al [ 77 ] highlighted the potential of COVID-19 to cause more severe febrile-induced seizures.…”