Complex bioelectric impedance measurement system for the frequency range from 5 Hz to 1 MHz

Ackmann, James J.

doi:10.1007/bf02367609

Cited by 103 publications

(67 citation statements)

References 2 publications

(1 reference statement)

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“…[48], processing steps are based on coherent demodulation principle, while synchronous sampling can be also employed [49], leading to good results. In both references, processing circuits must be synchronized with input signals, as a requirement for the technique to work, obtaining the best noise performance when proper filter functions (HP and LP) are incorporated.…”

Section: Bio-impedance Measurement Techniquesmentioning

confidence: 99%

“…The main drawback for in Ref. [48] is that the separated channels for in-phase and quadrature components must be matched to avoid large phase errors. Synchronous sampling proposed in Ref.…”

Section: Bio-impedance Measurement Techniquesmentioning

confidence: 99%

“…Excitation is usually done with AC current sources, while processing steps relies on algorithmic approaches, in order to decode the sample voltage response to signal excitation, the mission of the system described would be the effective determination of both bio-impedance components. Classical approaches consist on coherent demodulation principle [48] or synchronous sampling [49], leading, in general, to good results. In both techniques, processing circuits must be synchronized with input signals.…”

mentioning

confidence: 99%

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Towards Bio-impedance Based Labs: A Review

Pérez¹,

Maldonado²,

Yufera³

et al. 2016

JEE

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Abstract:In this article, some of the main contributions to BI (Bio-Impedance) parameter-based systems for medical, biological and industrial fields, oriented to develop micro laboratory systems are summarized. These small systems are enabled by the development of new measurement techniques and systems (labs), based on the impedance as biomarker. The electrical properties of the life mater allow the straightforward, low cost and usually non-invasive measurement methods to define its status or value, with the possibility to know its time evolution. This work proposes a review of bio-impedance based methods being employed to develop new LoC (Lab-on-a-Chips) systems, and some open problems identified as main research challenges, such as, the accuracy limits of measurements techniques, the role of the microelectrode-biological impedance modeling in measurements and system portability specifications demanded for many applications.

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Section: Bio-impedance Measurement Techniquesmentioning

confidence: 99%

“…The main drawback for in Ref. [48] is that the separated channels for in-phase and quadrature components must be matched to avoid large phase errors. Synchronous sampling proposed in Ref.…”

Section: Bio-impedance Measurement Techniquesmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Towards Bio-impedance Based Labs: A Review

Pérez¹,

Maldonado²,

Yufera³

et al. 2016

JEE

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“…Measurements were performed at room temperature in the frequency range from 100 kHz to 1 MHz using the 4284A HP LCR Meter [1,2,7,44].…”

Section: Electrical Measurementsmentioning

confidence: 99%

Physiological quality assessment of stored whole blood by means of electrical measurements

Ülgen

Sezdi

2007

Med Bio Eng Comput

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The physiological parameters of blood such as extracellular Na + , K + , Cl -, pH, 2,3-DPG and ATP and the complex electrical impedance were measured using whole blood samples from 31 male donors (21 donors form the training set and ten donors were used for testing), on the 0th, 10th and 21st day of blood bank storage. During storage, while the extracellular fluid resistance (R e ) and the intracellular fluid resistance (R i ) decreased progressively with time, the effective cell membrane capacitance (C m ) has increased. Blood bank storage resulted in a rise in K + and a fall in Na + , Cl -, pH, 2,3-DPG and ATP. Accordingly, all electrical parameters correlated with Na + , K + , Cl -, pH and ATP, at varying levels. By applying the multi-regression analysis, it was demonstrated that R i , R e and especially C m were appropriate for the assessment of Na + , K + , Cl -, pH and ATP until the 21st day of storage.

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“…Consequently, several designs and approaches to the design of current sources have been implemented and studied, e.g. current conveyors (Bragos et al 1994), floating-mirrored transconductance amplifiers (Ackmann 1993), Howlandbased topologies (Jossinet et al 1994) and negative impedance converters (NICs) (Lee et al 2006, Ross et al 2003.…”

Section: Introductionmentioning

confidence: 99%

Simple voltage-controlled current source for wideband electrical bioimpedance spectroscopy: circuit dependences and limitations

Seoane

Macias

Bardia

et al. 2011

Meas. Sci. Technol.

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In this work, the single Op-Amp with load-in-the-loop topology as a current source is revisited. This circuit topology was already used as a voltage-controlled current source (VCCS) in the 1960s but was left unused when the requirements for higher frequency arose among the applications of electrical bioimpedance (EBI). The aim of the authors is not only limited to show that with the currently available electronic devices it is perfectly viable to use this simple VCCS topology as a working current source for wideband spectroscopy applications of EBI, but also to identify the limitations and the role of each of the circuit components in the most important parameter of a current for wideband applications: the output impedance. The study includes the eventual presence of a stray capacitance and also an original enhancement, driving with current the VCCS. Based on the theoretical analysis and experimental measurements, an accurate model of the output impedance is provided, explaining the role of the main constitutive elements of the circuit in the source's output impedance. Using the topologies presented in this work and the proposed model, any electronic designer can easily implement a simple and efficient current source for wideband EBI spectroscopy applications, e.g. in this study, values above 150 k at 1 MHz have been obtained, which to the knowledge of the authors are the largest values experimentally measured and reported for a current source in EBI at this frequency.

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Complex bioelectric impedance measurement system for the frequency range from 5 Hz to 1 MHz

Cited by 103 publications

References 2 publications

Towards Bio-impedance Based Labs: A Review

Towards Bio-impedance Based Labs: A Review

Physiological quality assessment of stored whole blood by means of electrical measurements

Simple voltage-controlled current source for wideband electrical bioimpedance spectroscopy: circuit dependences and limitations

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