Completion of the rabies virus genome sequence determination: Highly conserved domains among the L (polymerase) proteins of unsegmented negative-strand RNA viruses

Tordo, Noël; Poch, Olivier; Ermine, Alain; Keith, Gérard; Rougeon, François

doi:10.1016/0042-6822(88)90600-9

Cited by 181 publications

(95 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Consensus sequences were aligned using the FFT-NS-i algorithm of MAFFT v. 6 [22]. Sequences were trimmed to equal length (760 nucleotides, encompassing the last 224 nucleotides of the glycoprotein gene, the G-L intergenic region and 118 nucleotides of the polymerase gene, based on the genome of the Pasteur rabies virus strain [23]). The overall mean distance between sequences in the alignment was calculated using MEGA v. 5 [24].…”

Section: (B) Rt-pcr and Sequencingmentioning

confidence: 99%

A Bayesian approach for inferring the dynamics of partially observed endemic infectious diseases from space-time-genetic data

et al. 2014

View full text Add to dashboard Cite

We describe a statistical framework for reconstructing the sequence of transmission events between observed cases of an endemic infectious disease using genetic, temporal and spatial information. Previous approaches to reconstructing transmission trees have assumed all infections in the study area originated from a single introduction and that a large fraction of cases were observed. There are as yet no approaches appropriate for endemic situations in which a disease is already well established in a host population and in which there may be multiple origins of infection, or that can enumerate unobserved infections missing from the sample. Our proposed framework addresses these shortcomings, enabling reconstruction of partially observed transmission trees and estimating the number of cases missing from the sample. Analyses of simulated datasets show the method to be accurate in identifying direct transmissions, while introductions and transmissions via one or more unsampled intermediate cases could be identified at high to moderate levels of case detection. When applied to partial genome sequences of rabies virus sampled from an endemic region of South Africa, our method reveals several distinct transmission cycles with little contact between them, and direct transmission over long distances suggesting significant anthropogenic influence in the movement of infected dogs.

show abstract

Section: (B) Rt-pcr and Sequencingmentioning

confidence: 99%

A Bayesian approach for inferring the dynamics of partially observed endemic infectious diseases from space-time-genetic data

et al. 2014

View full text Add to dashboard Cite

show abstract

“…This domain might be related to virus budding [8,11]. The highly conserved catalytic domains, typical for the L proteins of RABV, a member of the order Mononegavirales, are located between amino acids 587 and 811 [17,22]. Based on the result of amino acid sequence alignment, the highly conserved catalytic domain was found to be located between amino acids 563 and 786 of the L protein in SVCV A-1.…”

Section: Discussionmentioning

confidence: 99%

Characterization of complete genome sequence of the spring viremia of carp virus isolated from common carp (Cyprinus carpio) in China

et al. 2007

View full text Add to dashboard Cite

SummaryThe complete genome of spring viraemia of carp virus (SVCV) strain A-1 isolated from cultured common carp (Cyprinus carpio) in China was sequenced and characterized. Reverse transcriptionpolymerase chain reaction (RT-PCR) derived clones were constructed and the DNA was sequenced. It showed that the entire genome of SVCV A-1 consists of 11,100 nucleotide base pairs, the predicted size of the viral RNA of rhabdoviruses. However, the additional insertions in bp 4633-4676 and bp 4684-4724 of SVCV A-1 were different from the other two published SVCV complete genomes. Five open reading frames (ORFs) of SVCV A-1 were identified and further confirmed by RT-PCR and DNA sequencing of their respective RT-PCR products. The 5 structural proteins encoded by the viral RNA were ordered 3 0 -N-P-M-G-L-5 0 . This is the first report of a complete genome sequence of SVCV isolated from cultured carp in China. Phylogenetic analysis indicates that SVCV A-1 is closely related to the members of the genus Vesiculovirus, family Rhabdoviridae.

show abstract

“…É responsável pelas atividades enzimáticas necessárias à transcrição e replicação do RNA viral (TORDO et al, 1988).…”

Section: Lista De Figurasunclassified

Filogenia de vírus da raiva isolados de morcegos frugívoros do gênero Artibeus e relacionados a morcegos hematófagos com base nos genes codificadores da nucleoproteína N e glicoproteína G

Fahl¹

View full text Add to dashboard Cite

Completion of the rabies virus genome sequence determination: Highly conserved domains among the L (polymerase) proteins of unsegmented negative-strand RNA viruses

Cited by 181 publications

References 51 publications

A Bayesian approach for inferring the dynamics of partially observed endemic infectious diseases from space-time-genetic data

A Bayesian approach for inferring the dynamics of partially observed endemic infectious diseases from space-time-genetic data

Characterization of complete genome sequence of the spring viremia of carp virus isolated from common carp (Cyprinus carpio) in China

Filogenia de vírus da raiva isolados de morcegos frugívoros do gênero Artibeus e relacionados a morcegos hematófagos com base nos genes codificadores da nucleoproteína N e glicoproteína G

Contact Info

Product

Resources

About