Completion and Sensitivity of the Second‐Trimester Fetal Anatomic Survey in Obese Gravidas

Pasko, Daniel N.; Wood, S. Lindsay; Jenkins, Sheri M.; Owen, John

doi:10.7863/ultra.15.11057

Cited by 21 publications

(18 citation statements)

References 16 publications

(21 reference statements)

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“…Obstetric ultrasound is known to have limitations in this population (32,33). In one-quarter of mothers in this cohort, repeat midtrimester ultrasounds were required to complete the fetal anatomic survey because of poor visualization from maternal body habitus.…”

Section: Fetal Ultrasound Limitationsmentioning

confidence: 99%

Perinatal Outcomes in a Longitudinal Birth Cohort of First Nations Mothers With Pregestational Type 2 Diabetes and Their Offspring: The Next Generation Study

Pylypjuk

Sellers

Wicklow

2021

Canadian Journal of Diabetes

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Section: Fetal Ultrasound Limitationsmentioning

confidence: 99%

Perinatal Outcomes in a Longitudinal Birth Cohort of First Nations Mothers With Pregestational Type 2 Diabetes and Their Offspring: The Next Generation Study

Pylypjuk

Sellers

Wicklow

2021

Canadian Journal of Diabetes

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“…However, from the midwife’s perspective, the intention to identify the sex during a routine ultrasound is secondary to the medical examination. Determining the sex is sometimes difficult, depending on the weight of the woman and the position of the fetus, and the examination may therefore demand more time ( 34 ). Many parents want to know the sex, but the caregiver is only allowed to disclose the sex of the expected child if the pregnant woman expresses such a wish.…”

Section: Discussionmentioning

confidence: 99%

Do pregnant women want to know the sex of the expected child at routine ultrasound and are they interested in sex selection?

Larsson

Berglund

Jarl

et al. 2017

Upsala Journal of Medical Sciences

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BackgroundThe aim of the study was to investigate if expecting parents wanted to know the sex of the fetus during ultrasound examination and if they had discussed it with the midwife. Another aim was to explore any interest in sex selection.MethodsA longitudinal survey in early and late pregnancy among 2393 women in Sweden.ResultsAlmost all (95.8%, n = 2289) women had discussed sex determination with the partner before the ultrasound scan, and 57% (n = 1356) of women and their partners wanted to find out the fetal sex. The expecting parents mostly initiated a discussion with the midwife (46%, n = 1088), but 10% (n = 229) stated that the midwives initiated the discussion. Few (5%, n = 118) expressed a potential interest in selecting sex of a baby. Women who were interested in sex determination did not differ from those who were not, with respect to age, origin, education, parity, level of pregnancy planning, or importance of religion, but women who had chosen another fetal diagnostic method were more interested in sex determination and in potential sex selection.ConclusionsHalf of women and their partners wanted to know the fetal sex, and 5% were interested in sex selection. This high interest in sex determination is a challenge, since present national guidelines do not include sex determination as an option.

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“…One proposed mechanism is that high prepregnancy BMI decreases the likelihood of prenatal diagnosis of spina bifida via ultrasonography, decreases the likelihood of termination of pregnancy, and increases the probability that the liveborn case will be identified and included in the study (Peek & Nanan, 2009). This hypothesis is supported by studies that have found lower likelihood of prenatal diagnosis of birth defects among mothers with obesity, which makes the fetal anatomy difficult to visualize on ultrasound (Dashe, McIntire, & Twickler, 2009;Pasko, Wood, Jenkins, Owen, & Harper, 2016). This mechanism of selection bias is illustrated in Figure 1.…”

Section: Introductionmentioning

confidence: 99%

Prepregnancy body mass index and spina bifida: Potential contributions of bias

Johnson

Honein

Rasmussen

et al. 2021

Birth Defects Research

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Background: Epidemiologists have consistently observed associations between prepregnancy obesity and spina bifida in offspring. Most studies, however, used self-reported body mass index (potential for exposure misclassification) and incompletely ascertained cases of spina bifida among terminations of pregnancy (potential for selection bias). We conducted a quantitative bias analysis to explore the potential effects of these biases on study results. Methods: We included 808 mothers of fetuses or infants with spina bifida (case mothers) and 7,685 mothers of infants without birth defects (control mothers) from a population-based case-control study, the National Birth Defects Prevention Study (1997)(1998)(1999)(2000)(2001)(2002)(2003)(2004)(2005)(2006)(2007)(2008)(2009)(2010)(2011). First, we performed a conventional epidemiologic analysis, adjusting for potential confounders using logistic regression. Then, we used 5,000 iterations of probabilistic bias analysis to adjust for the combination of confounding, exposure misclassification, and selection bias. Results: In the conventional confounding-adjusted analysis, prepregnancy obesity was associated with spina bifida (odds ratio 1.4, 95% confidence interval: 1.2, 1.7). In the probabilistic bias analysis, we tested nine different models for the combined effects of confounding, exposure misclassification, and selection bias. Results were consistent with a weak to moderate association between prepregnancy obesity and spina bifida, with the median odds ratios across the nine models ranging from 1.1 to 1.4. Conclusions: Given our assumptions about the occurrence of bias in the study, our results suggest that exposure misclassification, selection bias, and confounding do not completely explain the association between prepregnancy obesity and spina bifida.

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Completion and Sensitivity of the Second‐Trimester Fetal Anatomic Survey in Obese Gravidas

Cited by 21 publications

References 16 publications

Perinatal Outcomes in a Longitudinal Birth Cohort of First Nations Mothers With Pregestational Type 2 Diabetes and Their Offspring: The Next Generation Study

Perinatal Outcomes in a Longitudinal Birth Cohort of First Nations Mothers With Pregestational Type 2 Diabetes and Their Offspring: The Next Generation Study

Do pregnant women want to know the sex of the expected child at routine ultrasound and are they interested in sex selection?

Prepregnancy body mass index and spina bifida: Potential contributions of bias

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