Complete XY gonadal dysgenesis and aspects of the SRY genotype and gonadal tumor formation

Uehara, Shigeki; Hashiyada, Masaki; Sato, Kosei; Nata, Masayuki; Funato, Tadao; Okamura, Koji

doi:10.1007/s100380200040

Cited by 42 publications

(34 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, it was similar to the 67% found in a more recent study (20), in which the sample was also formed only by patients with the complete form of the disease based on physical, endocrinological, surgical, and histopathological examinations. Those authors suggested that some patients classified as having ''gonadal dysgenesis'' in some previous reports may in fact have had the incomplete form or some other sex-reversal disorder characterized by female external genitalia and 46,XY karyotype (20). In addition, it must be considered that recent advances in the field of molecular genetics have allowed a more accurate analysis of the SRY gene.…”

Section: Discussionmentioning

confidence: 51%

Complete gonadal dysgenesis in clinical practice: the 46,XY karyotype accounts for more than one third of cases

Rocha

Guerra‐Júnior

Marques-de-Faria

et al. 2011

Fertility and Sterility

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 51%

Complete gonadal dysgenesis in clinical practice: the 46,XY karyotype accounts for more than one third of cases

Rocha

Guerra‐Júnior

Marques-de-Faria

et al. 2011

Fertility and Sterility

View full text Add to dashboard Cite

“…These patients can present with phenotypes ranging from streak gonads like those seen in Turner syndrome to genital ambiguity. One meta-analysis noted gonadal tumor formation in 52.5% of patients with SRY abnormalities (11).…”

Section: Genetic Causesmentioning

confidence: 99%

Is male infertility a forerunner to cancer?

et al. 2010

View full text Add to dashboard Cite

Purpose: The frequency of testicular cancer and male infertility has been increasing in the past several decades. This article examines the relationship between male infertility and testicular cancer, concentrating particularly on causal links. Results: Both of these disorders are associated with testicular dysgenesis syndrome and have also been traced to mutations in genes involving DNA repair and tumor suppression, as well as environmental exposure. Conclusion:The identification and examination of these common points of origin supports the integration of testicular cancer screenings into the routine evaluation of infertile men.

show abstract

“…The genetic variability results in a range of phenotypes which may be ambiguous or appear as male-or female-dominant (Donahoe et al, 1979). In complete gonadal dysgenesis, there is a proposed 30% risk of developing a malignancy (Uehara et al, 2002).…”

Section: Sex Chromosome Dsdmentioning

confidence: 99%

Textbook of Plastic and Reconstructive Surgery

Butler¹,

Ghali²,

Kalaskar³

2016

View full text Add to dashboard Cite

A CIP catalogue record for this book is available from The British Library.This book is published under a Creative Commons Attribution Non-commercial Non-derivative 4.0 International license (CC BY-NC-ND 4.0). This license allows you to share, copy, distribute and transmit the work for personal and non-commercial use providing author and publisher attribution is clearly stated. Further details about CC BY licenses are available at http://creativecommons.org/ licenses/by/4.0The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. The user is advised to always check the product information and clinical procedures with the most up-to-date published product information and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or misuse or misapplication of material in this work.ISBN: 978-1-910634-37-0 (Hbk.) ISBN: 978-1-910634-38-7 (Pbk.) ISBN: 978-1-910634-39-4 (PDF) ISBN: 978-1-910634-40-0 (epub) ISBN: 978-1-910634-41-7 (mobi)

show abstract

Complete XY gonadal dysgenesis and aspects of the SRY genotype and gonadal tumor formation

Cited by 42 publications

References 22 publications

Complete gonadal dysgenesis in clinical practice: the 46,XY karyotype accounts for more than one third of cases

Complete gonadal dysgenesis in clinical practice: the 46,XY karyotype accounts for more than one third of cases

Is male infertility a forerunner to cancer?

Textbook of Plastic and Reconstructive Surgery

Contact Info

Product

Resources

About