We have investigated tidal forces and geodesic deviation motion in the 4D-Einstein–Gauss–Bonnet spacetime. Our results show that tidal force and geodesic deviation motion depend sharply on the sign of Gauss–Bonnet coupling constant. Comparing with Schwarzschild spacetime, the strength of tidal force becomes stronger for the negative Gauss–Bonnet coupling constant, but is weaker for the positive one. Moreover, tidal force behaves like those in the Schwarzschild spacetime as the coupling constant is negative, and like those in Reissner–Nordström black hole as the constant is positive. We also present the change of geodesic deviation vector with Gauss–Bonnet coupling constant under two kinds of initial conditions.