Complete resolution of stage IIIB juvenile nasopharyngeal angiofibroma with radiation therapy

Abstract

Juvenile nasopharyngeal angiofi broma is a benign, locally aggressive, vascular tumour of adolescent males. Extension to intracranial cavity is not uncommon and presents diffi culties in management. Here we report a patient who had Radkowsky stage IIIB lesion, with blood supply from internal carotid artery. In view of anticipated problems with surgery, the patient was treated with 30 Gy in 15# external beam radiotherapy. On follow up, tumour was noted to disappear gradually overtime and at 3 years complete disappearance was noted with normal return of vision. Hence we are re-affi rming the earlier studies than angiofi broma mass regresses gradually after completion of radiotherapy. Radiotherapy is a useful way of treating angiofi broma with signifi cant intracranial extension.

Radiation-Induced Sarcoma Originating in Recurrent Juvenile Nasopharyngeal Angiofibroma

“…Conley et al also reported a case of orbital squamous cell carcinoma [10]. Only two studies have reported sarcomatous change in JNA postirradiation [11, 12], though possibility of the same have been put forth by many studies [4, 13]. As in our patient, radiotherapy has been used in the adjuvant setting as well.…”