Complete remission of relapsing eosinophilic fasciitis associated with bronchial asthma following regular steroid inhalation

Yamanishi, Yasuhito; Ishioka, Shinichi; Yamakido, Michio

doi:10.1093/rheumatology/39.3.339

Cited by 7 publications

(6 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Through the review of the literature, there is only one other case by Yamanishi where recurrent asthma has been seen to be associated with eosinophilic fasciitis [8]. To the knowledge of the authors of this paper, this patient represents the second recorded incident.…”

Section: Discussionmentioning

confidence: 94%

See 1 more Smart Citation

Orthopedic Considerations with Eosinophilic Fasciitis: A Case Report and Literature Review

Samona

2012

Case Reports in Orthopedics

View full text Add to dashboard Cite

Eosinophilic fasciitis (EF) or Shulman's disease is a very rare condition first described in 1974 by Dr. Shulman in patients with diffuse fasciitis and eosinophilia. Fewer than 300 cases have been reported worldwide in the past 35 years. The current understanding of the disease in the medical community relies only on a few large case series and multiple case reports. The proposed etiology, pathological mechanisms, and consensus for therapy are obscure or lacking. The presentation of the disease is variable, but certain signs and symptoms have been associated with EF. The extreme rarity of the disease, the large constellation of signs and symptoms, as well as the lack of knowledge about eosinophilic fasciitis and make this disease difficult to recognize and treat. Through the review of the literature, there is only one other case by Yamanishi where recurrent asthma has been seen to be associated with eosinophilic fasciitis. To the knowledge of the authors of this paper this patient represents the second recorded incident. The case described by the authors of this paper demonstrated an initial biopsy of mixed cell fasciitis including eosinophils, compared to the eosinophil-rich sample taken at a later date. This could be a unique aspect to the pathology of the disease not previously discovered. Similar scenarios were not noted in a review of the literature. A change in the pathological findings as shown in this case from non-eosinophil-rich sample to one rich in eosinophils is unique in a patient actively suffering from EF. The authors of this paper propose that an allergic reaction (at the patient's puncture site) occurred, which initially caused the left hand symptoms that led to the patient's first presentation to the hospital. This is a unique causative agent, not found in the review of the literature. Through a review of the literature and the presentation of this patient, the authors propose an underlying dysregulation of the immune system, leading to the initiation or synergistic perpetuation of EF. This is a unique outlook on the disease pathology, not explained much in the medical literature.

show abstract

Section: Discussionmentioning

confidence: 94%

“…Other potential triggers include exposure to toxins, environmental, trauma, arthropod bites, and borreliosis [2]. In the review of literature, only one case report was found to claim association between relapsing eosinophilic fasciitis and bronchial asthma [8]. …”

Section: Introductionmentioning

confidence: 99%

Orthopedic Considerations with Eosinophilic Fasciitis: A Case Report and Literature Review

Samona

2012

Case Reports in Orthopedics

View full text Add to dashboard Cite

show abstract

“…Some patients have presented with rapidly progressive muscle weakness with associated pain and stiffness of the extremities 2 . A variety of extracutaneous manifestations have been reported including arthritic, pulmonary, hematologic, and neoplastic 4–6 . The diagnosis of eosinophilic fasciitis may be delayed, as it has overlapping features of other diseases.…”

Section: Introductionmentioning

confidence: 99%

“…2 A variety of extracutaneous manifestations have been reported including arthritic, pulmonary, hematologic, and neoplastic. [4][5][6] The diagnosis of eosinophilic fasciitis may be delayed, as it has overlapping features of other diseases. Scleroderma, polymyositis, hypereosinophilic syndrome, and Churg-Strauss vasculitis may all be in the differential diagnosis for a patient presenting with eosinophilic fasciitis.…”

Section: Introductionmentioning

confidence: 99%

Eosinophilic fasciitis: demographics, disease pattern and response to treatment: report of 12 cases and review of the literature

2007

View full text Add to dashboard Cite

Background Eosinophilic fasciitis is a rare scleroderma-like illness. The clinical spectrum of the disease has evolved since its initial description. MethodsWe identified all patients diagnosed with eosinophilic fasciitis over the past 10 years at our scleroderma clinic. Demographics, disease pattern, serologies, tissue pathology and reponse to treatment were all recorded.Results Twelve patients with eosinophilic fasciitis were identified in our clinic over the past 10 years. The mean age at diagnosis was 49.8 ± 9.8 years, with nine female and three male patients. The first symptoms were noticed at an average of 8.8 ± 6.1 months before diagnosis.The mean initial absolute peripheral blood eosinophil count was 1188 ± 1059 cells/L. Two patients had a monoclonal gammopathy, and two had positive ANA titers. All patients received corticosteroids, 10 of whom received the equivalent dose of > 20 mg/day of prednisone for more than a month. Five patients received hydroxychloroquine, two received methotrexate, one received cyclosporine, one received topical tacrolimus, and one received sulfasalazine.At a mean follow up of 17.6 months (range 2-94 months), 8 patients had a good response to treatment, 2 patients had no effect, and 2 patients had a poor response to treatment. ConclusionHigh dose corticosteroid treatment lasting longer than a month with or without an immunosuppressive agent helped most patients with eosinophilic fasciitis, best results seen in those patients who were initiated treatment early on after their first symptoms.

show abstract

“…Sclerodactyly, nail-fold capillary changes, internal organ involvement and RP are rare and help differentiate EF from SSc. EF may be associated with inflammatory arthritis, and pulmonary, haematological and neoplastic disorders [7][8][9]. Laboratory findings are variable and may include hypergammaglobulinaemia, peripheral blood eosinophilia and elevated acute-phase reactants.…”

Section: Introductionmentioning

confidence: 99%

Infliximab may be effective in the treatment of steroid-resistant eosinophilic fasciitis: report of three cases

2010

View full text Add to dashboard Cite

show abstract

Complete remission of relapsing eosinophilic fasciitis associated with bronchial asthma following regular steroid inhalation

Cited by 7 publications

References 2 publications

Orthopedic Considerations with Eosinophilic Fasciitis: A Case Report and Literature Review

Orthopedic Considerations with Eosinophilic Fasciitis: A Case Report and Literature Review

Eosinophilic fasciitis: demographics, disease pattern and response to treatment: report of 12 cases and review of the literature

Infliximab may be effective in the treatment of steroid-resistant eosinophilic fasciitis: report of three cases

Contact Info

Product

Resources

About