2004
DOI: 10.1080/08880010490500962
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COMPLETE PLATELET RECOVERY AFTER TREATMENT OFHELICOBACTER PYLORIINFECTION IN A CHILD WITH CHRONIC IMMUNE THROMBOCYTOPENIC PURPURA: A Case Report

Abstract: Helicobacter pylori gastritis has been associated with autoimmune disease, including immune thrombocytopenic purpura (ITP). The most recent reports also have supported this association in adults. ITP in children differs from that in adults in terms of clinical picture and mechanisms of thrombocytopenia. The authors report a case of a 12-year-old boy with chronic ITP, in whom they detected H. pylori infection and observed a complete platelet recovery after the eradication of H. pylori.

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Cited by 18 publications
(6 citation statements)
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“…Worldwide, an association between ITP and H. pylori has been found in 11 single‐case reports: five in the European continent with three in Italy [69–71], one in Spain [72] and one in Turkey [73], and six in the Asian continent, all in Japan [74–79]. Also, until now, 23 series have been reported: in the European continent there are nine reported series [12–19,80] with a total of 414 patients with ITP, 258 (62.3%) were infected with H. pylori .…”
Section: Discussionmentioning
confidence: 99%
“…Worldwide, an association between ITP and H. pylori has been found in 11 single‐case reports: five in the European continent with three in Italy [69–71], one in Spain [72] and one in Turkey [73], and six in the Asian continent, all in Japan [74–79]. Also, until now, 23 series have been reported: in the European continent there are nine reported series [12–19,80] with a total of 414 patients with ITP, 258 (62.3%) were infected with H. pylori .…”
Section: Discussionmentioning
confidence: 99%
“…Besides the tests already suggested in the guidelines for acute ITP, the Helicobacter pylori evaluation is recommended to exclude the infective nature of thrombocytopenia (8.8 – A) [29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45]. The stool antigen test is preferable because it is simple, cheap and comparable to the urea breath test [46,47,48].…”
Section: Resultsmentioning
confidence: 99%
“…The medical literature subsequently reported similar cases in Japan [142][143][144][145][146], Italy [147][148][149], and Turkey [150].…”
Section: H Pylori and Immune Thrombocytopeniamentioning
confidence: 99%