Complete Oculomotor Palsy after Influenza Vaccination in a Young Healthy Adult: A Case Report

Abstract

Influenza vaccines are known to have a few neurological complications, such as Guillain-Barre syndrome, chronic inflammatory demyelinating polyneuropathy, and acute disseminated encephalomyelitis. However, oculomotor palsy caused by influenza vaccination is extremely rare. We present a case report of a 25-year-old woman without any medical history who developed complete oculomotor palsy 2 weeks after influenza vaccination. Other possible causes of oculomotor nerve palsy, such as stroke, compressive lesions, infections, and autoimmune disorders, were eliminated by blood tests, cerebrospinal fluid examination, and imaging studies. Hence, influenza vaccine was considered as the likely cause.

Ocular Complications Following Vaccination for COVID-19: A One-Year Retrospective

“…Vaccination-induced cranial nerve palsies have previously been reported following the influenza, hepatitis B, smallpox, and MMR vaccines [124][125][126][127][128][129][130]. While the exact mechanism has not been elucidated, vaccine-induced cranial nerve palsies are believed to be due to immune-mediated damage resulting in demyelination or vascular compromise resulting in reduced blood flow [130,131].…”

Tolosa-Hunt syndrome associated with coronavac / Sinovac vaccination against Covid-19

“…This vaccine is known to cause Guillain-Barre syndrome, demyelinating polyneuropathy, and disseminated encephalomyelitis, among others. 6 A case of Tolosa-Hunt syndrome was reported most recently, however, this was with mRNA-based Covid-19 vaccine. 7 This continues the discussion on the side effects of vaccines against Covid-19, whether exacerbating previously acquired unknown conditions, or being the cause of such.…”