Complete Hydatidiform Mole with Coexisting Twin Fetus: Usefulness of MRI in Management Planning

Bajaj, Sharad; Misra, Ritu; Gupta, Rohini; Nisha, B; Thukral, Brij Bhushan

doi:10.1007/s13224-012-0346-2

Cited by 7 publications

(9 citation statements)

References 10 publications

(10 reference statements)

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“…The incidence of CHMCF is predicted to rise in the future, as the ultrasonographic technology used in detecting CHMCF advances and the extensive use of ovulation induction techniques increases [12,59,103]. 29.94% (n = 50) of the pregnancies in the present literature review were conceived with the aids of several assisted conception methods (Table 2).…”

Section: Discussionmentioning

confidence: 95%

“…167 cases were discovered and their findings were summarized in Tables 1 (Ref. [3,5,6,12,) and Table 2.…”

Section: Discussionmentioning

confidence: 99%

“…With the recent advances in ultrasonography, CHMCF can even be incidentally detected starting late in the first trimester [103,108]. In this condition, the complete mole typically presents with a classical snowstorm appearance together with the presence of a normal placenta and a viable fetus [4,7,12,103,110]. Occasionally, a theca lutein cyst is detected on ultrasound due to a significantly elevated level of serum beta-hCG, suggesting a higher probability of CHMCF [45,103,109,111,112].…”

Section: Discussionmentioning

confidence: 99%

“…Complete hydatidiform mole with a coexistent fetus (CHMCF) can result in a viable fetus that may survive until delivery [2,3]. However, the management of patients with CHMCF is difficult due to its rarity and complexity [7,[10][11][12]. Although the fetus in CHMCF can be alive [2,3], the pregnancy is usually terminated due to consequences that can threaten the lives of both the mother and fetus [2,3,[13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

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Successful delivery of a twin pregnancy with complete hydatidiform mole and coexistent live fetus: a case report and review of literature

Sethi¹,

Tan²,

Kamarudin³

et al. 2021

Clinical and Experimental Obstetrics & Gynecology

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Background: A twin pregnancy consisting of either a complete or partial hydatidiform mole and a fetus is rare. The reported incidence ranges from 1:22,000-100,000 pregnancies, and complete hydatidiform mole with a coexistent fetus (CHMCF) comprises the majority of these cases. The management of CHMCF is controversial, as maternal risk with continuation of the pregnancy should be weighed against fetal survival. Women with CHMCF are at risk of developing preeclampsia, gestational diabetes, hyperthyroidism, antepartum hemorrhage, and gestational trophoblastic neoplasia. Case: We report a case of a healthy 32-year-old woman in her third pregnancy. She presented at 18 weeks gestation with vaginal bleeding and a significantly large uterus relative to the gestational age. Ultrasound showed CHMCF with a beta-hCG value of 398,800 IU/L. After careful discussion with the patient and after considering her options, she elected to continue the pregnancy. She was closely monitored for complications and had no maternal or fetal concerns. An elective cesarean delivery was performed at 32 weeks. A live female infant was delivered together with a normal placenta and a complete mole. The mother and baby were discharged in good condition after 2 days. A histopathological examination of the molar tissue confirmed the CHMCF diagnosis. No finding of gestational trophoblastic neoplasia (GTN) was discovered throughout one-year follow-up. Conclusion: Successful pregnancy outcomes can be achieved in cases of CHMCF. Comprehensive counseling with the patient regarding possible complications is important. Closely monitoring the mother for any complications and performing ongoing fetal surveillance are essential. Delivery should be planned at a tertiary center with good facilities and neonatal support.

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Section: Discussionmentioning

confidence: 95%

“…167 cases were discovered and their findings were summarized in Tables 1 (Ref. [3,5,6,12,) and Table 2.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Successful delivery of a twin pregnancy with complete hydatidiform mole and coexistent live fetus: a case report and review of literature

Sethi¹,

Tan²,

Kamarudin³

et al. 2021

Clinical and Experimental Obstetrics & Gynecology

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show abstract

“…This condition is rare, with an estimated incidence of 1 to 20,000–100,000 pregnancies ( 5 ) . Although the etiopathogenesis of this type of gestation is unclear, several studies have found a correlation of twin pregnancy with a hydatidiform mole and a coexisting live fetus with clinical complications typical of late hydatidiform moles more frequently than in single moles, thus increasing the risk of potentially fatal complications and a near miss ( 6 , 7 ) .…”

Section: Introductionmentioning

confidence: 99%

A twin pregnancy with a hydatidiform mole and a coexisting live fetus: prenatal diagnosis, treatment, and follow-up

et al. 2017

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Twin molar pregnancy with a hydatidiform mole and a coexisting live fetus is a rare form of gestational trophoblastic disease associated with an increased risk of obstetric complications and poor perinatal outcome. Prenatal diagnosis is essential for couple counseling and follow-up in Tertiary Reference Centers. Magnetic resonance imaging is important for the diagnostic differentiation of placental mesenchymal dysplasia and exclusion of myometrial invasion. Here we present a case of twin molar pregnancy with a hydatidiform mole and a coexisting live fetus diagnosed at gestational week 14 using two-dimensional (2D) and three-dimensional (3D) ultrasound and magnetic resonance imaging. We also describe the obstetric management and postmolar follow-up.

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Imaging of Placental Pathology

Prins

Sebire

Khalil

et al. 2021

Benirschke's Pathology of the Human Placenta

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Complete Hydatidiform Mole with Coexisting Twin Fetus: Usefulness of MRI in Management Planning

Cited by 7 publications

References 10 publications

Successful delivery of a twin pregnancy with complete hydatidiform mole and coexistent live fetus: a case report and review of literature

Successful delivery of a twin pregnancy with complete hydatidiform mole and coexistent live fetus: a case report and review of literature

A twin pregnancy with a hydatidiform mole and a coexisting live fetus: prenatal diagnosis, treatment, and follow-up

Imaging of Placental Pathology

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