Complete Genome Sequencing of
            <i>Acinetobacter</i>
            sp. Strain LoGeW2-3, Isolated from the Pellet of a White Stork, Reveals a Novel Class D Beta-Lactamase Gene

Blaschke, Ulrike; Skiebe, Evelyn; Kaatz, Michael; Higgins, Paul G.; Pfeifer, Yvonne; Wilharm, Gottfried

doi:10.1128/genomea.01405-17

Cited by 1 publication

(1 citation statement)

References 12 publications

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“…The high genetic diversity and genomic plasticity within Acinetobacter may be driven by mechanisms facilitating horizontal gene transfer (HGT), including competence for natural transformation (9)(10)(11)(12), conjugative abilities, and prevalent mobile elements such as plasmids, prophage, and insertion sequences (8,13,14). Horizontally acquired genomic islands are common observed throughout the Acinetobacter genus (15,16) and can contain genes conferring beneficial phenotypes like antibiotic resistance and plasmid mobilization (17,18). HGT is a source of evolutionary novelty in bacteria (19), but other sources of genetic diversity can also be important, such as error-prone polymerases in A. baumannii (4,8,20), or gene duplication followed by divergence (21).…”

Section: Introductionmentioning

confidence: 99%

Genome evolution following an ecological shift in nectar-dwellingAcinetobacter

Sanchez,

Renner,

Baker

et al. 2023

Preprint

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The bacterial genusAcinetobacterincludes species found in environmental habitats like soil and water, as well as species adapted to be host-associated or pathogenic. High genetic diversity may allow for this habitat flexibility, but the specific genes underlying switches between habitats are poorly understood. One lineage ofAcinetobacterhas undergone a substantial habitat change by evolving from a presumed soil-dwelling ancestral state to thrive in floral nectar. Here we compared the genomes of floral-dwelling and pollinator-associatedAcinetobacter, including newly described species, with genomes from relatives found in other environments to determine the genomic changes associated with this ecological shift. Following one evolutionary origin of floral nectar adaptation, nectar-dwellingAcinetobacterspecies have undergone reduction in genome size compared to relatives and have experienced dynamic gene gains and losses as they diversified. We found changes in gene content underlying carbohydrate metabolism and nitrogen metabolism, which we predict to be beneficial in nectar environments. Gene losses follow a pattern consistent with genome streamlining, whereas gains appear to result from both evolutionary divergence and horizontal gene transfer. Most notably, nectar-dwellingAcinetobacteracquired the ability to degrade pectin from plant pathogens and the genes underlying this ability have duplicated and are under selection within the clade. We hypothesize that this ability was a key trait for adaptation to floral nectar, as it could improve access to nutrients in the nutritional unbalanced habitat of nectar. These results identify the genomic changes and traits coinciding with a dramatic habitat switch from soil to floral nectar.

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