Complete Genome Sequence of Wohlfahrtiimonas chitiniclastica Strain SH04, Isolated from Chrysomya megacephala Collected from Pudong International Airport in China

Abstract

Wohlfahrtiimonas chitiniclastica bacilli that live in the larvae of a parasitic fly were recently isolated and are speculated to be the cause of fulminant sepsis. Here we report and analyze the complete genome sequence of Wohlfahrtiimonas chitiniclastica strain SH04. No complete genome sequence of a Wohlfahrtiimonas chitiniclastica isolate has been documented previously.

Wohlfahrtiimonas chitiniclastica: current insights into an emerging human pathogen

“…[1]. Furthermore, another publication about the pathogen's occurrence in the insect species Hermetia illucens [3] and a report on a whole genome sequence of a W. chitiniclastica strain [11] appeared. To date, seven case reports and in total eight cases have been published on W. chitiniclastica infections in humans (case numbers: 1 [4], 2 [6], 3 [12], 4 [7], 5 [13], 6 [14], 7, 8 [15]).…”

“…The sequenced W. chitiniclastica strain SH04 has a genome size of 2·12 Mb, with an average G/C content of 43·48%. It contains 2006 open reading frames [11]. Further investigations revealed a high similarity to I. larvae , another bacterial species which is also commonly found in flies [1, 5].…”

“…MIC values ranged from 0•032 μg/ml to 4 µg/ml, except for fosfomycin, which revealed MIC values >1024 µg/ml in all isolates presented in Table 3. [11].…”

Wohlfahrtiimonas chitiniclasticaBacteremia Associated with Myiasis, United Kingdom

“…This bacterium has been isolated from larvae of the fly Wohlfahrtia magnifica, a serious parasite of livestock in eastern Europe, the Mediterranean, and Central Asia ( 3 ), but this fly is not usually seen in the United Kingdom. W. chitiniclastica has also been isolated in China from Chrysomya megacephala oriental latrine flies, a screwworm species common in tropical and subtropical regions that is a facultative cause of myiasis ( 4 , 5 ). A study from South Korea reported a new Wohlfahrtiimonas sp.…”

Complete Genome Sequence of Wohlfahrtiimonas chitiniclastica Strain BM-Y, Isolated from the Pancreas of a Zebra in China

“…To date, five Wohlfahrtiimonas species and no more than 20 W. chitiniclastica strains have been isolated in the world. Of these, only antibiotic sensitive strain SH04 has been sequenced completely in China ( 6 ).…”