Complete genome sequence of bacteriocin-producing Lactobacillus plantarum KLDS1.0391, a probiotic strain with gastrointestinal tract resistance and adhesion to the intestinal epithelial cells

Jia, Fang-Fang; Zhang, Lu-Ji; Pang, Xue-Hui; Gu, Xiaosong; Abdelazez, Amro; Yu, Liang; Sun, Su-Qin; Meng, Xiang-Chen

doi:10.1016/j.ygeno.2017.06.008

Cited by 65 publications

(37 citation statements)

References 48 publications

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“…Different gene products perform specific biological functions together through orderly coordination. KEGG annotation have abundant access information could achieve function message, such as metabolic pathway, genetic information transmission, and cytological process (Avrani, Wurtzel, Sharon, Sorek, & Lindell, ; Jia et al., ). For WHH1689, metabolism had a large proportion in histogram of KEGG.…”

Section: Resultsmentioning

confidence: 99%

Genomic analysis of Lactobacillus reuteri WHH1689 reveals its probiotic properties and stress resistance

Chen

et al. 2019

Food Science & Nutrition

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Lactobacillus reuteri (L. reuteri) WHH1689, which was isolated from Chinese traditional highland barley wine, exhibited high survival period at room temperature in drinkable probiotic yogurt. This article aimed to indicate the genes involved in probiotic function of WHH1689 and reveal potential stress resistance based on genomic analysis. Analysis of comparative genome with closely related L. reuteri strains identified special stress adaptation. MUMmer and ACT softwares were applied for collinear analysis, and OrthoMCL program was used for sequence alignment involved in distribution of protein cluster. We identified genes coding for carbohydrate transport and enzymes, carbon metabolism pathway, gastrointestinal tract resistance, adhesive ability, and folic acid biosynthesis, etc. Genome sequence and comparative genome analysis of L. reuteri WHH1689 demonstrated specific genes for genetic adaptation and stress resistance. Tolerance, adhesion, and folate test indicated the strain had multiple probiotics. L. reuteri WHH1689 has the potential to be a probiotic candidate in dairy foods.

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Section: Resultsmentioning

confidence: 99%

Genomic analysis of Lactobacillus reuteri WHH1689 reveals its probiotic properties and stress resistance

Chen

et al. 2019

Food Science & Nutrition

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“…The extracellular proteins of lactobacilli play important roles mediating interactions with the host or the environment [25]. Cell surface proteins of strain WiKim0068 include glyceraldehyde-3-phosphate dehydrogenase, triosephosphate isomerase, trehalose and maltose hydrolases (possible phosphorylases), beta-galactosidase, lipoprotein signal peptidase, and sortase (surface protein transpeptidase), which have been implicated in adhesion or binding to other cells [26]. The amino acid metabolism-related genes of strain WiKim0068 were annotated using the KEGG database.…”

Section: Adhesion Ability Amino Acid and Nicotinate And Nicotinamidmentioning

confidence: 99%

Characterization of a potential probiotic bacterium Lactococcus raffinolactis WiKim0068 isolated from fermented vegetable using genomic and in vitro analyses

Jung¹,

Lee²,

Seo

et al. 2020

Preprint

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Background: Lactococcus members belonging to lactic acid bacteria are widely used as starter bacteria in the production of fermented dairy products. From kimchi, a Korean food made of fermented vegetables, Lactococcus raffinolactis WiKim0068 was isolated and its genome was analyzed. Results: The complete genome of the strain WiKim0068 consists of one chromosome and two plasmids that comprises 2,292,235 bp, with a G+C content of 39.7 mol%. Analysis of orthoANI values among Lactococcus genome sequences showed that the strain WiKim0068 has > 67% sequence similarity to other species and subspecies. In addition, it displayed no antibiotic resistance and can metabolize nicotinate and nicotinamide (vitamin B3). Conclusion: These results augments our understanding of the genus Lactococcus and suggest that this new strain has potential industrial applications.

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“…Fifty-two of the proteins are predicted to be potentially surface exposed, some of which have a confirmed role in adhesion, e.g. the moonlighting triose phosphate isomerase, elongation factor Tu, glyceraldehyde-3-phosphate dehydrogenase, three mucus binding proteins and three fibronectin-binding proteins [ 72 ]. Further, GADPH and triose phosphate isomerase were reported in L. plantarum 423 to play a role in adhesion and competitive exclusion of pathogens [ 73 ].…”

Section: Adhesion Factors Of Lactobacillimentioning

confidence: 99%

Dietary Nutrients, Proteomes, and Adhesion of Probiotic Lactobacilli to Mucin and Host Epithelial Cells

Çelebioğlu

Svensson

2018

Microorganisms

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The key role of diet and environment in human health receives increasing attention. Thus functional foods, probiotics, prebiotics, and synbiotics with beneficial effects on health and ability to prevent diseases are in focus. The efficacy of probiotic bacteria has been connected with their adherence to the host epithelium and residence in the gut. Several in vitro techniques are available for analyzing bacterial interactions with mucin and intestinal cells, simulating adhesion to the host in vivo. Proteomics has monitored and identified proteins of probiotic bacteria showing differential abundance elicited in vitro by exposure to food components, including potential prebiotics (e.g., certain carbohydrates, and plant polyphenols). While adhesion of probiotic bacteria influenced by various environmental factors relevant to the gastrointestinal tract has been measured previously, this was rarely correlated with changes in the bacterial proteome induced by dietary nutrients. The present mini-review deals with effects of selected emerging prebiotics, food components and ingredients on the adhesion of probiotic lactobacilli to mucin and gut epithelial cells and concomitant abundancy changes of specific bacterial proteins. Applying this in vitro synbiotics-like approach enabled identification of moonlighting and other surface-located proteins of Lactobacillus acidophilus NCFM that are possibly associated with the adhesive mechanism.

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Complete genome sequence of bacteriocin-producing Lactobacillus plantarum KLDS1.0391, a probiotic strain with gastrointestinal tract resistance and adhesion to the intestinal epithelial cells

Cited by 65 publications

References 48 publications

Genomic analysis of Lactobacillus reuteri WHH1689 reveals its probiotic properties and stress resistance

Genomic analysis of Lactobacillus reuteri WHH1689 reveals its probiotic properties and stress resistance

Characterization of a potential probiotic bacterium Lactococcus raffinolactis WiKim0068 isolated from fermented vegetable using genomic and in vitro analyses

Dietary Nutrients, Proteomes, and Adhesion of Probiotic Lactobacilli to Mucin and Host Epithelial Cells

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