Complete Genome Sequence of Achromobacter xylosoxidans Myophage Mano

Abstract

Achromobacter spp. are ubiquitous Gram-negative bacteria, some of which can cause respiratory tract infections in patients with autoimmune disorders and cystic fibrosis. Bacteriophages have therapeutic and biotechnological potential to combat Achromobacter sp. infections. This announcement details the 42.5-kb genome sequence of the temperate Achromobacter xylosoxidans myophage Mano.

Analysis of a Novel Bacteriophage vB_AchrS_AchV4 Highlights the Diversity of Achromobacter Viruses

“…To date, a total of 20 Achromobacter species and 24 genogroups belong to this genus [7,8]; however, knowledge on bacteriophages targeting this bacterium is still scarce. While a number of published reports of Achromobacter phages may be found in the literature [9][10][11][12][13][14][15][16][17], nearly all describe viruses that are lytic against Achromobacter xylosoxidans, the type species of the genus. To date, there have been no reports of bacteriophages active on Achromobacter spanius.…”

Characterisation of New Foxunavirus Phage Murka with the Potential of Xanthomonas campestris pv. campestris Control

“…A BLAST search using sequences of Murka’s sequences indicated that Foxunavirus phages were the closest relatives. The search also found related phages infecting bacteria, other than Xanthomonas , including Burkholderia phage Mica (genus Micavirus ) [ 60 ], Achromobacter phage Mano (genus Manovirus ) [ 61 ], Acinetobacter phage Alexa (unclassified), Escherichia phage vB_EcoM-ep3 (genus Jilinvirus ) [ 62 ], and Serratia phage MQ-4 (unclassified) [ 63 ]. The results of comparative genome alignment showed a similarity of genomic organization between these phages, Foxunavirus phages, and phage Murka ( Figure 6 ).…”