Let M be a compact Kähler manifold and N be a subvariety with codimension greater than or equal to 2. We show that there are no complete Kähler-Einstein metrics on M − N . As an application, let E be an exceptional divisor of M . Then M − E cannot admit any complete Kähler-Einstein metric if blow-down of E is a complex variety with only canonical or terminal singularities. A similar result is shown for pairs. Problem 1.1. Let M be a compact Kähler manifold and N be a subvariety with codimension bigger than or equal to 2, how to find a complete canonical metric on the noncompact Kähler manifold M − N ? Date: March 22, 2016.