Complementary and Alternative Medicine Use for Treatment and Prevention of Late-Life Mood and Cognitive Disorders

Lavretsky, Helen

doi:10.2217/1745509x.5.1.61

Cited by 52 publications

(55 citation statements)

References 108 publications

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“…17 Other herbal preparations that show some efficacy in treating depression include S-adenosyl-methionine (SAMe) and St. John's wort. 5 The relationship between SAMe and depression has been studied for several decades. 3 SAMe is suggested to be an effective depression treatment that is comparable to tricyclic antidepressants, with quicker action and fewer adverse effects.…”

Section: Solbergmentioning

confidence: 99%

“…4 There has been growing interest in complementary and alternative medicine for a variety of medical conditions, including depression. 3,5,6 Approximately 44% of psychiatric inpatients have used an herbal preparation to treat a variety of symptoms. 7 Egg components have a variety of physiologic effects, including novel antimicrobial, immunomodulatory, anticancer, and antihypertensive activities; antioxidant properties; protease-inhibiting ability; and nutrient bioavailability.…”

Section: Introduction Dmentioning

confidence: 99%

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The Effects of Powdered Fertilized Eggs on Depression

Solberg

2011

Journal of Medicinal Food

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This 12-week, double-blind, placebo-controlled study investigated the effects of fertilized egg powder (Young Tissue Extract; YTE Ò ) intake on outcome measures for depression. Fifty-five patients with depression were randomly assigned to receive YTE, YTE plus Melissa officinalis, or placebo for 12 weeks. At baseline, there were no significant differences in scores on the Hamilton Depression Rating Scale (HAM-D) or Beck Depression Inventory II (BDI-II) among the 3 groups. At 12 weeks, the HAM-D scores in groups treated with YTE or YTE with M. officinalis were both significantly lower than those in the placebo group. In addition, both treatment groups showed a significant improvement in depression as measured by the change in HAM-D scores from baseline to 12 weeks, whereas the placebo group showed no significant change. There were no significant differences between the 2 treatment groups. The study indicates that the fertilized egg powder has an antidepressive effect and may be an alternative or adjunct to antidepressive medication for some patients, but further research is necessary.

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Section: Solbergmentioning

confidence: 99%

Section: Introduction Dmentioning

confidence: 99%

The Effects of Powdered Fertilized Eggs on Depression

Solberg

2011

Journal of Medicinal Food

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“…Mindfulness in this setting promotes self-awareness in a noncompetitive, non-judgmental environment and at the same time promotes awareness of muscular movements, alignment, mental states and breath. 44 Increased levels of mindfulness were found after yoga in a healthy population 45 and a chronic illness population. 17 A mindfulness assessment was included in this study to evaluate the potential to develop increased mindfulness in the AYT.…”

Section: Introductionmentioning

confidence: 99%

Yoga for persons with severe visual impairment: a feasibility study

et al. 2012

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This exploratory study aims to establish the feasibility of an Ashtanga-based Yoga Therapy (AYT) program for improving sleep disturbances, balance, and negative psychosocial states, which are prevalent issues for visually impaired (VI) individuals. Ten legally blind adult participants were randomized to an 8-week AYT program. Four subjects in the 1 st cohort and three in the 2 nd cohort successfully completed the AYT program. They convened for one session per week with an instructor and performed two home-based sessions per week using an audio CD. The Pittsburgh Sleep Quality Index (PSQI), Perceived Stress Scale (PSS), Beck Anxiety Inventory (BAI), and Beck Depression Inventory (BDI) were administered at baseline and post-intervention. A Timed One-Leg balance measure, respiratory rate (RR), and the Philadelphia Mindfulness Scale (PHLMS) were assessed in the 2 nd cohort. Both groups completed a qualitative exit survey. Positive exit survey responses (all subjects were extremely or mostly satisfied, and wanted to continue AYT) and good participation rates (7 subjects attended at least 7 of the 8 weekly sessions) support the feasibility of the AYT. PSQI, PSS, BAI and BDI scores changed in the direction of reduced negative symptoms after AYT for the 1 st cohort. Changes in PSQI and PSS for the 2 nd cohort were varied. Balance, RR and PHLMS awareness trended toward improvement for each individual. This preliminary study provides proof of concept for potential benefits of AYT that may be observed in VI subjects. Larger studies and an active control group are needed to determine efficacy.

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“…• Cofactor in NT synthesis • methylation homocysteine → methionine RCTs are mixed (47)(48)(49); B9 is an effective adjunct (50)(51)(52) RCTs are mixed; when no deficiency exists, more robust response in those without dementia (56)(57)(58) • Increased total mortality risk in meta-analysis (59) a Adapted from Lavretsky (67). Abbreviations: AD-Alzheimer's disease; NSAID-Nonsteroidal anti-inflammatory drug; SAMe-S-adenosyl-L-methionine; SSRI -Serotoninspecific reuptake inhibitor; RCT-Randomized controlled trial; VAD -vascular dementia; GI-gastrointestinal; 5-HT-serotonin; NT-neurotransmitter; HA-headaches CONCLUSION Late-life mood and cognitive disorders are among the most common reasons for older adults to use CAM practices (Table 1).…”

Section: Cognitive Disordersmentioning

confidence: 99%

The Use of Natural Products and Supplements in Late-Life Mood and Cognitive Disorders

Varteresian¹,

Merrill²,

Lavretsky³

2013

FOC

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Natural products and supplements are widely and increasingly used by the aging population for mood and cognitive symptoms. Evidence suggests that some supplements may be effective at treating a range of mood and cognitive symptoms. There is growing use of complementary and alternative medicine in the treatment of mental disorders because they may be seen as "safer" than traditional drugs, and because patients with mental disorders frequently use complementary and alternative medicine. We review the existing limited evidence of the efficacy and safety of natural products and supplements that are being used for treatment of mental disorders. More rigorous studies in the area of holistic and integrative treatment and preventive approaches for late-life mood and cognitive disorders are urgently needed.

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Complementary and Alternative Medicine Use for Treatment and Prevention of Late-Life Mood and Cognitive Disorders

Cited by 52 publications

References 108 publications

The Effects of Powdered Fertilized Eggs on Depression

The Effects of Powdered Fertilized Eggs on Depression

Yoga for persons with severe visual impairment: a feasibility study

The Use of Natural Products and Supplements in Late-Life Mood and Cognitive Disorders

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