Complementary and Alternative Medicine in Psychotic Disorders

Hazra, Monica; Noh, Samuel; Boon, Heather; Taylor, Andree; Moss, Karen; Mamo, David C.

doi:10.2202/1553-3840.1239

Cited by 7 publications

(8 citation statements)

References 18 publications

(41 reference statements)

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“…In a community-based study in Turkey on the use of TCM, it was found that 58% of participants had recourse to TCM, while in another study 22.2% of psychiatric outpatients used them 11,12 . Research in other countries on mental disorders and TCM, rates of use were given as 34-88% 13,14,15 . In the United States, a community-based study was conducted on TCM use at three different time points between 2002 and 2012.…”

Section: Discussionmentioning

confidence: 99%

Psikiyatri polikliniğine başvuran hastalarda geleneksel ve tamamlayıcı tıp uygulamalarının özellikleri ve yaygınlığı

Bal

Cengisiz

Yılmaz³

et al. 2017

Cukurova Medical Journal (Çukurova Üniversitesi Tıp Fakültesi Dergisi)

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The aim of this study was to determine the variables in the use of traditional and complementary medicine for psychiatric complaints in and around the city of Adana, in Turkey's Eastern Mediterranean region. Material and Methods: The study was performed with 1768 psychiatric outpatients of Çukurova, Kozan and Ceyhan State Hospitals in Adana who gave written approval and fitted the criteria. The structured clinical interview for DSM-5 was performed by a psychiatrist, and a questionnaire was given to gather socio-demographic information and clinical details on the use of traditional and complementary medicine. Results: The proportion of participants using some kind of traditional and complementary medicine was found to be 39.7%. Those mostly used were, in order of frequency, prayer and consultation (16%), herbal products (10.5%), and nutritional supplements (7.1%). Regarding the perceived effectiveness of the use of traditional and complementary medicine, 68.6% of participants reported that they were partially or greatly effective. The use of traditional and complementary medicine was greater among the elderly, those living in rural areas, those with a low income, and those with a low education level. Conclusion: The results of our study show that the use of traditional and complementary medicine among the mentally ill is widespread, and it is important that physicians and policy-makers should be aware this fact. Amaç: Bu çalışmanın amacı, Türkiye'nin Doğu Akdeniz Bölgesindeki Adana ili ve çevresinde, psikiyatrik yakınmalarda geleneksel ve tamamlayıcı tıp kullanımındaki değişkenleri belirlemektir. Gereç ve Yöntem: Bu çalışma, Adana ilindeki Çukurova, Kozan ve Ceyhan Devlet Hastaneleri psikiyatri polikliniklerine ayaktan başvuran, katılma ölçütlerini karşılayan ve yazılı onam veren 1768 hasta ile yürütülmüştür. DSM-5 için yapılandırılmış klinik görüşme psikiyatrist tarafından yapılmıştır. Sosyodemografik bilgiler ile geleneksel ve tamamlayıcı tıp uygulamalarındaki klinik ayrıntıların toplanılması için bir anket formu verilmiştir. Bulgular: Herhangi bir geleneksel ve tamamlayıcı tıp uygulamasına başvuran katılımcı oranı %39.7 idi. En çok kullanılanlar, sıklık sırasına göre; dua ve danışma (%16), bitkisel ürünler (%10.5) ve besin ekleriydi (%7.1). Geleneksel ve tamamlayıcı tıp uygulamasının algılanan etkinliği açısından bakıldığında, katılımcıların %68.6'sı kısmen ya da büyük oranda etkili bulduğunu bildirmiştir. Verilerimize göre yaşlılarda, kırsal kesimde yaşayanlarda, düşük gelir grubunda ve düşük eğitim düzeyinde geleneksel ve tamamlayıcı tıp kullanımı daha fazladır. Sonuç: Çalışmamız, rusal hastalığı olanlarda geleneksel ve tamamlayıcı tıp kullanımının yaygın olduğunu göstermiştir. Hekimlerin ve politika belirleyicilerin bu durumun bilincinde olmaları önem taşımaktadır.

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Section: Discussionmentioning

confidence: 99%

Psikiyatri polikliniğine başvuran hastalarda geleneksel ve tamamlayıcı tıp uygulamalarının özellikleri ve yaygınlığı

Bal

Cengisiz

Yılmaz³

et al. 2017

Cukurova Medical Journal (Çukurova Üniversitesi Tıp Fakültesi Dergisi)

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“…Foong Xi Wei, Anand Gaurav, Mayasah Al-Nema treatment or medications in the hope of minimising the unwanted adverse effects. Nonconventional treatment includes alternative and complementary medicine and therapeutic lifestyle changes (Hazra et al, 2010). Natural medicine is a part of complementary medicine that based on utilizing natural drugs produced by living organisms i.e.…”

Section: In Silico Investigation On the Probable Macromolecular Drug ...mentioning

confidence: 99%

In silico investigation on the probable macromolecular drug targets involved in the anti-schizophrenia activity of Nardostachys jatamansi

Wei

Gaurav

Al-Nema

2022

Braz. J. Pharm. Sci.

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Existing medications i.e. the antipsychotic drugs are known to be effective in treating only the positive symptoms of schizophrenia, while being ineffective on negative and cognitive symptoms of the disease. In addition, these medications cause extrapyramidal symptoms, forcing many patients towards natural medicine in the hope of minimising the unwanted adverse effects. Nardostachys jatamansi is a medicinal plant that has been traditionally prescribed for various types of brain disorders. The active constituents of the plant have beneficial effects on the negative and cognitive symptoms of schizophrenia. This study was designed to identify the active constituents of Nardostachys jatamansi with the highest binding affinities for the key macromolecular drug targets involved in the pathophysiology of schizophrenia and thereby elucidate the possible mechanism of action. These targets are dopamine receptors, Gammaaminobutyric acid receptors, N-methyl-D-aspartate receptors and Phosphodiesterase 10A. The results of molecular docking showed that, β-sitosterol, chlorogenic acid, oleanic acid and ursolic acid, displayed high binding affinity toward all the macromolecular drug targets. Ligands with steroid backbone and pentacyclic triterpene structure have been found to possess high binding affinity toward the dopamine receptor and phosphodiesterase 10A. While ligands with carbonyl group form stronger binding interactions with the N-methyl-D-aspartate receptor.

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“…20 Many patients with psychotic disorders use nonconventional medicines like therapeutic lifestyle changes and complementary and alternative medicine in the hope of decreasing undesired adverse effects or a more successful recovery. [21][22][23][24][25][26][27][28][29] Lambert and Castle have recommended in their report that 'though medication is a vital part of treatment for most people with schizophrenia, it can be complemented by many of the other options such as traditional and alternative treatment in most people with schizophrenia'. 31 Homoeopathy can be a useful treatment option in psychiatric cases as it treats patient holistically taking mind and body into account.…”

Section: Introductionmentioning

confidence: 99%

Homoeopathic Add-On Treatment in Schizophrenia—A Case Report

et al. 2022

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Introduction Schizophrenia is a chronic disabling disease which requires lifelong treatment. Antipsychotics are the mainstay of treatment as of now, which are very expensive and known to cause many side effects. It would be favourable if alternative treatment options like homeopathy are brought into limelight in the treatment of schizophrenia. Very sparse literature is available evaluating the utility of individualised homoeopathic medicine in the this condition. Methods A 33-year-old woman presenting with symptoms of schizophrenia and under conventional medication was treated during a period of April 2019 to October 2020. Individualised homoeopathic medicine was prescribed as add-on therapy. Outcomes were assessed using Positive and Negative Syndrome Scale. Side effects of antipsychotics were assessed using Glasgow Antipsychotics Side-effects Scale. Modified Naranjo Criteria was used to assess whether the changes were likely to be associated with the homoeopathic intervention. Results A beneficial result was obtained from individualised homoeopathic treatment. The antipsychotic medication was stopped within 9 months of treatment. Conclusion More studies with large sample size are required to provide additional support to this study.

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Complementary and Alternative Medicine in Psychotic Disorders

Cited by 7 publications

References 18 publications

Psikiyatri polikliniğine başvuran hastalarda geleneksel ve tamamlayıcı tıp uygulamalarının özellikleri ve yaygınlığı

Psikiyatri polikliniğine başvuran hastalarda geleneksel ve tamamlayıcı tıp uygulamalarının özellikleri ve yaygınlığı

In silico investigation on the probable macromolecular drug targets involved in the anti-schizophrenia activity of Nardostachys jatamansi

Homoeopathic Add-On Treatment in Schizophrenia—A Case Report

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