Complementary and alternative medicine for <scp>A</scp>lzheimer's disease: an overview of systematic reviews

Posadzki, Paul; Ernst, Edzard; Lee, Myeong Soo

doi:10.1111/fct.12001

Cited by 5 publications

(3 citation statements)

References 13 publications

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“…−1 means that none of the above criteria were fulfilled. This is operationalisation of the Oxman criteria, adapted from Posadzki, Ernst and Lee (2012) …”

Section: Resultsmentioning

confidence: 99%

Complementary and alternative medicine for the prevention and treatment of migraine headache: an overview of systematic reviews

Posadzki

Al-Bedah

Khalil³

et al. 2015

Focus on Alt & Comp Therapy

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Background Complementary and alternative medicine (CAM) is very popular among migraineurs. Objectives The aim of this article is to summarise and critically evaluate the evidence from systematic reviews (SRs) of CAM for the prevention and treatment of migraine headache. Method Ten electronic databases were searched from 1946 to August 2014. Retrieved papers were also hand‐searched for relevant references. Systematic reviews were eligible for inclusion if they reported the prevention and treatment of migraine headache using any type of CAM. Oxman criteria were used to appraise the methodological quality of the included SRs. Results Thirty‐three SRs, with a total of 45 886 migraine sufferers, were included in the analyses. The majority (64%) of the SRs were of high methodological quality (mean Oxman score=4.87, SD=3.96). Most (60.6%) SRs arrived at positive conclusions (16 of which were of high quality); two (6.0%) SRs arrived at negative conclusions (of which one was of high quality), and 11 (33.3%) arrived at equivocal conclusions (of which four were of high quality). The majority of the high‐quality SRs (Oxman score=6–9) were based on moderate‐quality RCTs. For multiple SRs, unanimously positive conclusions were reached for acupuncture and biofeedback. There was conflicting evidence regarding the effectiveness of homeopathy, herbal medicines such as Petasites hybridus and Tanacetum parthenium L., and spinal manipulative therapy. Conclusion The evidence from SRs evaluating the effectiveness of CAM for the prevention or treatment of migraine headache is mostly positive. However, several caveats should be taken into account, and only for acupuncture and biofeedback are the conclusions unanimously positive.

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“…−1 means that none of the above criteria were fulfilled. This is operationalisation of the Oxman criteria, adapted from Posadzki, Ernst and Lee (2012) …”

Section: Resultsmentioning

confidence: 99%

Complementary and alternative medicine for the prevention and treatment of migraine headache: an overview of systematic reviews

Posadzki

Al-Bedah

Khalil³

et al. 2015

Focus on Alt & Comp Therapy

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“…There was a lack of sufficient data in the reviews on quality of life. Posadzki, Ernst, and Lee (2012) conducted an overview on SRs of the complementary and alternative medicine for Alzheimer's disease and the authors found Ginkgo biloba (ginkgo) in high‐dose (240 mg) effective for cognition improvement and QOL but there was no high quality SR to support the effectiveness of Hup A on. AD, and eventually authors proposed further studies on alternative medicine in the future for management of AD.…”

Section: Discussionmentioning

confidence: 99%

The effects of Huperzine A on dementia and mild cognitive impairment: An overview of systematic reviews

Ghassab-Abdollahi

Mobasseri

Ahmadabad

et al. 2021

Phytotherapy Research

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Cognitive impairments are a part of the neurocognitive disorders which deteriorate the normal cognitive function. An overview of systematic reviews (SRs) was conducted to summarize the findings of SRs and meta‐analyses on the effectiveness of Huperzine A (Hup A) in dementia and mild cognitive impairment (MCI). A literature search was conducted since inception to December 2020. We used the AMSTAR tool to assess the methodological quality of SRs. The quality of evidence of primary studies was evaluated according to the SRs authors' assessment. Six SRs met our inclusion criteria. The results showed that Hup A has beneficial effects on cognitive function and Activities of Daily Living (ADLs) in Alzheimer's disease, but in vascular dementia and MCI, there was little or no evidence to conclusion. There is insufficient evidence of the effectiveness of Hup A on the quality of life and global clinical assessment. None of the SRs reported any serious side effects. Despite the promising effects of Hup A on cognition and ADLs, there is insufficient evidence to support the effectiveness of Hup A in cognitive impairments due to the high heterogeneity of SRs and the low quality of primary studies. High‐quality, large multicenter RCTs with long‐term follow‐up in different settings are warranted.

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“…It is characterised by many features such as the deterioration of structure and/or function of neurons associated with functional disorders of language, memory, cognition, emotion, character and behaviour (Ip, Tsim et al 2014;Liu, Kong et al 2014). It has been reported that traditional herbal medicine products are the most popular CAM modality for this condition in comparison to other CAM-based therapies (Posadzki, Ernst et al 2012). …”

Section: Cam and Alzheimer's Diseasementioning

confidence: 99%

Natural Products & Complementary Medicines: where are we up to?

Alqathama

2016

British Journal of Pharmacy

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Complementary and alternative medicine for Alzheimer's disease: an overview of systematic reviews

Cited by 5 publications

References 13 publications

Complementary and alternative medicine for the prevention and treatment of migraine headache: an overview of systematic reviews

Complementary and alternative medicine for the prevention and treatment of migraine headache: an overview of systematic reviews

The effects of Huperzine A on dementia and mild cognitive impairment: An overview of systematic reviews

Natural Products & Complementary Medicines: where are we up to?

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