Complementary/alternative medicine in the treatment of asthma

Graham, Donna Melissa; Blaiss, Michael S.

doi:10.1016/s1081-1206(10)62569-0

Cited by 39 publications

(14 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The observed differences in popularity of different CAM modalities are most likely a factor of the different cultural and ethnic groups being assessed. For example, given the relative salience of religion in the African-American community (45), it is not surprising that the use of prayer was relatively high in our sample of mostly African-American adolescents-a finding echoed in other studies of adult CAM use (46). Our study was one of the few (41,47) to report which specific CAM modalities adolescents with asthma would consider using in the future for symptom managementthe top three in this study being relaxation, prayer, and massage.…”

Section: Discussionsupporting

confidence: 63%

Complementary and Alternative Medicine Behaviors and Beliefs in Urban Adolescents with Asthma

Cotton

Luberto

et al. 2011

Journal of Asthma

View full text Add to dashboard Cite

Many urban adolescents used and would consider using CAM, specifically relaxation and prayer, for asthma symptom management. African-Americans, older adolescents, and those with more frequent symptoms were more likely to use and/or consider using CAM. Providers caring for urban adolescents with asthma should discuss CAM with patients, particularly those identified as likely to use CAM. Future studies should examine relationships between CAM use and health outcomes.

show abstract

Section: Discussionsupporting

confidence: 63%

Complementary and Alternative Medicine Behaviors and Beliefs in Urban Adolescents with Asthma

Cotton

Luberto

et al. 2011

Journal of Asthma

View full text Add to dashboard Cite

show abstract

“…To date, no scientific study has been reported that has examined alternative therapies in connection with the development or persistence of TDI-induced asthma in rats. However, the use of complementary and alternative medicines for asthma treatment is of great interest in patient care (Lane and Lane, 1991;Graham and Blaiss, 2000). To this goal, we have selected this herbal plant to reveal its scientific exploration for the treatment of asthma.…”

Section: Introductionmentioning

confidence: 99%

Effect ofMoringa oleiferaLam. Seed Extract on Toluene Diisocyanate-Induced Immune-Mediated Inflammatory Responses in Rats

Mahajan

Mali

Mehta

2007

Journal of Immunotoxicology

View full text Add to dashboard Cite

Moringa oleifera Lam. is a small tree cultivated throughout India. We have investigated the effect of ethanolic extract of seeds of Moringa oleifera (MOEE, an herbal remedy) on the potential prevention of immune-mediated inflammatory responses in toluene diisocyanate (TDI as antigen)-induced asthma in Wistar rats. Rats were divided into five different groups (n = 8/group): Group-I = unsensitized control; Group-II = TDI control/vehicle; Group-III = dexamethasone (DXM) 2.5 mg/kg; and, Groups IV and V = 100 mg/kg and 200 mg/kg body weight [BW] of MOEE, respectively. All rats (except unsensitized controls) were sensitized by intranasal application of 10% TDI to induce airway hypersensitivity. Animals in Groups II-V were given their respective drug treatment per os from 1 wk prior to initiation of sensitization until the day of final provocation with 5% TDI. After this last challenge, all rats were examined for hyperreactivity symptoms and then sacrificed to determine their total and differential leucocytes in blood and bronchoalveolar (BAL) fluid and levels of TNF∝, IL-4, and IL-6 in their BAL and serum. Homogenates of one lung lobe from each animal were utilized to assess oxidative stress; a separate lobe underwent histologic examination to assess airway inflammatory status. The results suggest that asthmatic symptoms were found in TDI control rats only, while both MOEE-and DXM-treated rats did not manifest any airway abnormality. In MOEE-and DXM-treated rats, neutrophil and eosinophil levels in the blood were decreased significantly; levels of total cells and each different cell in their BAL fluid were markedly decreased as compared to those in TDI controls. TNFα, IL-4, and IL-6 were predominant in serum as well as in BAL fluids in TDI controls, but these levels were reduced significantly by MOEE treatment. The antioxidant activity in relation to antiinflammatory activity of the extract and histopathological observations also reflected a protective effect. Based on the above findings and observations, it can be concluded that Moringa oleifera may possess some beneficial properties that act against chemically stimulated immune-mediated inflammatory responses that are characteristic of asthma in the rat.

show abstract

“…Prior research on CAM use in asthma showed fairly high prevalence rates of CAM use among children (Braganza, Ozuah, & Sharif, 2003;Crawford, Cincotta, Lim, & Powell, 2006;Mazur, DeYbarrondo, Miller, & Colasurdo, 2001;Reznik, Ozuah, Franco, Cohen, & Motlow, 2002;Shenfield, Lim, & Allen, 2002) yet the results of studies on CAM therapies do not generally support their efficacy in treating asthma (Angsten, 2000;Bielory, 2004;Bielory, Russin, & Zuckerman, 2004;Blazek-O'Neill, 2005;Gardnier & Wornham, 2000;Graham & Blaiss, 2000;Gyorik & Brutsche, 2004;Heimall & Bielory, 2004;Markham & Wilkinson, 2004). CAM prevalence rates (lifetime and current) among children with asthma range from 52% to 89% (Braganza et al; Mazur et al; Reznik et al; Shenfield et al).…”

mentioning

confidence: 99%

Don't Ask, Don't Tell: Parental Nondisclosure of Complementary and Alternative Medicine and Over-the-Counter Medication Use in Children's Asthma Management

Sidora-Arcoleo¹,

Yoos²,

Kitzman³

et al. 2008

Journal of Pediatric Health Care

View full text Add to dashboard Cite

show abstract

Complementary/alternative medicine in the treatment of asthma

Cited by 39 publications

References 30 publications

Complementary and Alternative Medicine Behaviors and Beliefs in Urban Adolescents with Asthma

Complementary and Alternative Medicine Behaviors and Beliefs in Urban Adolescents with Asthma

Effect ofMoringa oleiferaLam. Seed Extract on Toluene Diisocyanate-Induced Immune-Mediated Inflammatory Responses in Rats

Don't Ask, Don't Tell: Parental Nondisclosure of Complementary and Alternative Medicine and Over-the-Counter Medication Use in Children's Asthma Management

Contact Info

Product

Resources

About