Complaints of insomnia in hospitalized alcoholics

Escobar-Córdoba, Franklin; Ávila-Cadavid, Juan David; Cote-Menéndez, Miguel

doi:10.1590/s1516-44462009000300013

Cited by 20 publications

(24 citation statements)

References 11 publications

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“…Insomnia is more prevalent in women in the general population (Krystal, 2003;Klink, Quan, Kaltenborn, & Lebowitz, 1992 ), which was found in this study as well, whereas at least two other studies of AD patients failed to find such a difference Escobar-Córdoba et al, 2009). The latter two studies, however, were mostly inpatients, a status that may be associated with gender-independent illness severity.…”

Section: Discussionsupporting

confidence: 73%

“…As with quantity of alcohol consumption, some (Baekeland, et al, 1974;Brower et al, 2001;Foster & Peters, 1999), but not all (Cohn et al, 2003;Escobar-Córdoba et al, 2009) studies of AD patients have found that depressive symptoms are a correlate of insomnia. In samples of populations who are not alcohol dependent, depression and insomnia are highly comorbid and persistent (Staner, 2010).…”

Section: Discussionmentioning

confidence: 99%

“…Across 11 studies with a range from 36% to 91%, a mean of 59.4% of 3,027 AD patients endorsed symptoms of insomnia (Baekeland, Lundwall, Shanahan, & Kissin, 1974;Bokstrom & Balldin, 1992;Brower, Aldrich, Robinson, Zucker, & Greden, 2001;Caetano, Clark, & Greenfield, 1998;Cohn, Foster, & Peters, 2003;Escobar-Córdoba,Ávila-Cadavid, & Cote-Menendez, 2009;Feuerlein, 1974;Foster & Peters, 1999;Mello & Mendelson, 1970;Perney, Lehert, & Mason, 2012;Zhabenko, Wojnar, & Brower, 2012). This prevalence is comparable to insomnia rates in primary care settings (Leger, Partinen, Hirshkowitz, Chorkoverty, & Hedner, 2010;Shochat, Umphress, Israel, & Ancoli-Israel, 1999), but higher than in the general population, where approximately one-third of adults have reported one or more symptoms of insomnia in the past 6-12 months (Calem et al, 2012;Roth et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

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A Longitudinal Study of Drinking and Depression as Predictors of Insomnia in Alcohol-Dependent Individuals

Zhabenko

Krentzman

Robinson

et al. 2013

Substance Use & Misuse

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Insomnia and depressive symptoms are common symptoms among alcohol-dependent (AD) patients. AD individuals (N = 364) were assessed during 2004-2009 in the Midwestern United States at baseline and 6-month intervals with the Sleep Problems Questionnaire, Time-Line Follow-Back interview, and the depression subscale of the Brief Symptom Inventory. Hierarchical Linear Modeling was used to analyze the data in this longitudinal study. When modeled separately, both quantity of drinking (p < .01) and depression (p < .001) predicted insomnia severity, controlling for time, age, and gender. Drinking also predicted depressive symptoms (p < .001), and its effect on insomnia was mediated by depression severity (p < .001).

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Section: Discussionsupporting

confidence: 73%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A Longitudinal Study of Drinking and Depression as Predictors of Insomnia in Alcohol-Dependent Individuals

Zhabenko

Krentzman

Robinson

et al. 2013

Substance Use & Misuse

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“…Our respondents confirmed that substance use undermines sleep quality and quantity (Arnedt et al, 2012;Burke et al, 2008;Escobar-Cordoba et al, 2009;Hasler et al, 2014), but also revealed that poor sleep can persist even after substance use has reduced or ceased. The types of sleep problems identified were diverse; as were accounts of the causes of, and strategies for dealing with, those problems.…”

Section: Discussionsupporting

confidence: 69%

“…Illicit and non-medical psychoactive substance use is linked to poor sleep quality and quantity (Arnedt et al, 2012;Burke et al, 2008;Escobar-Cordoba et al, 2009;Hasler et al, 2014). Nonetheless, there is limited qualitative research on substance users' subjective experiences of sleep.…”

Section: Introductionmentioning

confidence: 99%

Substance use, sleep and intervention design: insights from qualitative data

Neale

Meadows

Nettleton

et al. 2017

Journal of Mental Health

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Background: Alcohol and other drug use is associated with poor sleep quality and quantity, but there is limited qualitative research exploring substance users' experiences of sleep and few psychosocial sleep interventions for them. Aim: To inform the development of psychosocial interventions to improve sleep amongst people reporting drug/alcohol problems. Method: Qualitative data were collected during a sleep survey. Of the 549 drug/alcohol users completing the survey, 188 (34%) provided additional information about their sleep using a free text box. Responses were analysed via Iterative Categorisation. Findings were reviewed with reference to the Behaviour Change Wheel (BCW). Results: All data were categorised inductively under five headings: (i) sleep quality; (ii) nature of sleep problems; (iii) sleep and substances; (iv) factors improving sleep quality; (v) factors undermining sleep quality. Substance use undermined sleep, but poor sleep often persisted after substance use had ceased. Sleep problems were diverse; as were the causes of, and strategies for dealing with, those problems. Causes and strategies had biological, psychological, social and environmental roots. Conclusions: The BCW facilitated the identification of intervention components that might improve the sleep of people who use substances. These components relate to education, training, enablement, modelling, service provision, guidelines and environment.

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The dual orexin receptor antagonist suvorexant in alcohol use disorder and comorbid insomnia: A case report

Campbell,

Bonomo,

Collins

et al. 2024

Clinical Case Reports

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Key Clinical MessageThis case suggests using dual orexin receptor antagonists to treat alcohol use disorder and comorbid sleep disorders may be effective, commencing treatment in withdrawal and continuing it to prevent relapse.AbstractEffective medications for the treatment of alcohol use disorder are limited. This is partially due to the heterogenous nature of the symptomatology associated with alcohol use disorder and the abundance of presenting comorbidities. One common, and often overlooked, symptom that occurs during withdrawal of alcohol use is sleep disruption. Here, we report a case study of a participant with comorbid alcohol use disorder and insomnia. This participant was treated with a dual orexin receptor antagonist, suvorexant (Belsomra®), currently approved to treat insomnia. We demonstrate improvements in alcohol cravings, physical and psychological health, and sleep outcomes with treatment. These data support abundant preclinical and emerging clinical data in this space. The findings from this case report highlight the potential for suvorexant to treat comorbid alcohol use disorder and insomnia with fully powered, randomized controlled trials moving forward.

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Complaints of insomnia in hospitalized alcoholics

Cited by 20 publications

References 11 publications

A Longitudinal Study of Drinking and Depression as Predictors of Insomnia in Alcohol-Dependent Individuals

A Longitudinal Study of Drinking and Depression as Predictors of Insomnia in Alcohol-Dependent Individuals

Substance use, sleep and intervention design: insights from qualitative data

The dual orexin receptor antagonist suvorexant in alcohol use disorder and comorbid insomnia: A case report

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