Competent F18 bioglass-Biosilicate® bone graft scaffold substitutes

Antimicrobial characteristics of the Li2O–ZrO2–Si2O bioactive glass and glass‐ceramic for bone regeneration and wound healing

“…36 A concentration of 50 mg/mL of the F18 SiO 2 -Na 2 O-K 2 O-MgO-CaO-P 2 O 5 bioglass promoted inhibition of CFUs of S. aureus (ATCC 6538 and ATCC 25923), E. coli (ATCC 8739P), and P. aeruginosa (ATCC 27853). 43,44 With an exposure time of 6 days, 1000 mg/mL of BAG S53P4 1.0−2.0 mm inhibited the growth of P. aeruginosa (ATCC 27853) and the same MBC against S. aureus (ATCC 29213), after 7 days of exposure. 45 Considering the different experimental procedures used in previous studies, LZS glass and LZS glass-ceramic showed a faster and more effective bactericidal effect than other bioactive glasses.…”

“…The antimicrobial activity of different bioactive glasses has been tested in other studies, such as 45S5 Bioglass (in wt%) 45% SiO 2 , 24.5% Na 2 O, 24.5% CaO, and 6% P 2 O 5 , in which a 24‐h contact with the microorganism resulted in an MBC of 50 mg/mL against S. aureus (ATCC 25923) and E. coli (ATCC 25922) 36 . A concentration of 50 mg/mL of the F18 SiO 2 –Na 2 O–K 2 O–MgO–CaO–P 2 O 5 bioglass promoted inhibition of CFUs of S. aureus (ATCC 6538 and ATCC 25923), E. coli (ATCC 8739P), and P. aeruginosa (ATCC 27853) 43,44 . With an exposure time of 6 days, 1000 mg/mL of BAG S53P4 1.0−2.0 mm inhibited the growth of P. aeruginosa (ATCC 27853) and the same MBC against S. aureus (ATCC 29213), after 7 days of exposure 45 .…”