The aims of this study were: to assess cognitive and mood problems, perceived social support and coping strategies in adolescence and early adulthood; to understand how coping strategies are related to age, gender and years of schooling; to identify possi- ble stable and modifiable predictors of cognitive and mood problems adopting LISREL software. The participants were 517 adolescents and young adults (age M = 18.95 years, SD = 3.2, range: 14 - 25); 59% were female and with a mean of 13.10 years of schooling (SD = 2.7). Participants were enrolled in secondary schools, association groups or university in Veneto, Italy. They completed a battery of self-report ques- tionnaires via a secure online site or in paper versions. The LISREL model was psy- chometrically solid and showed good fit (χ2 = 15.96, df = 12, p = 0.19, RMSEA = 0.025), explaining 26% of the variance and showing how the stable factor gender and some modifiable factors, namely certain coping strategies and friends’ support, pre- dicted cognitive and mood problems