Compatibility of Calycosin-Tanshinone IIA improves Ang II-induced renal artery endothelial cell dysfunction through lncRNA-mRNA coexpression network
Jiang YanYun,
Han Cong,
Xu WanLi
et al.
Abstract:Background
Long noncoding RNAs (lncRNAs) have been found to have a significant impact on the development of endothelial dysfunction. Nevertheless, the precise mechanism underlying the compatibility of Calycosin-Tanshinone IIA in mitigating the dysfunction of rat renal artery endothelial cells (RRAECs) through the coexpression network of lncRNA-mRNA remains uncertain.
Methods
In the present investigation, an experimental model of endothelial cell injury was established by subjecting RRAECs to Ang II (5×10− 7m… Show more
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