Compassionate use of roxadustat for treatment of refractory renal anemia in an infant
Yan Yang,
Yan Chen,
Yang Yang
et al.
Abstract:Background
Erythropoiesis-stimulating agents (ESAs) have played an important role in the treatment of renal anemia in children, but cannot improve hemoglobin to target level in some cases. Roxadustat, a hypoxia-inducible factor prolyl hydroxylase inhibitor, can stimulate endogenous erythropoietin production and regulate iron metabolism even in patients with kidney failure. However, roxadustat has not yet been approved for use in children.
Case–diagnosis/Treatment
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