In this paper, we consider a comparison of estimation methods for the parameters of Xgamma Weibull distribution. It is discussed five different estimation methods such as maximum likelihood method, least-squares method, weighted least-squares method, the method of Anderson-Darling and the method of Crámer-von-Mises. We compare these estimators via Monte Carlo simulations according to the biases and mean-squared errors (MSEs). Further, seven real data applications are conducted and Kolmogorov Smirnov goodness of fit test is also calculated for all estimators.