Comparison the efficacy of hemorrhage control of Surgiflo Haemostatic Matrix and absorbable gelatin sponge in posterior lumbar surgery

Ma, Litai; Dai, Lijuan; Yang, Yi; Liu, Hao

doi:10.1097/md.0000000000013511

Cited by 29 publications

(23 citation statements)

References 17 publications

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“…93 All have been deemed relatively safe, and in the authors' experience, they are all effective at safely reducing blood loss. 94 A summary of the most commonly employed agents and their efficacy is presented in Table 4.…”

Section: Topical Hemostatic Agentsmentioning

confidence: 99%

Minimizing Blood Loss in Spine Surgery

Mikhail

Pennington

Arnold

et al. 2020

Global Spine Journal

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Study Design: Broad narrative review. Objective: To review and summarize the current literature on guidelines, outcomes, techniques and indications surrounding multiple modalities of minimizing blood loss in spine surgery. Methods: A thorough review of peer-reviewed literature was performed on the guidelines, outcomes, techniques, and indications for multiple modalities of minimizing blood loss in spine surgery. Results: There is a large body of literature that provides a consensus on guidelines regarding the appropriate timing of discontinuation of anticoagulation, aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), and herbal supplements prior to surgery. Additionally, there is a more heterogenous discussion the utility of preoperative autologous blood donation facilitated by erythropoietin and iron supplementation for healthy patients slated for procedures with high anticipated blood loss and for whom allogeneic transfusion is likely. Intraoperative maneuvers available to minimize blood loss include positioning and maintaining normothermia. Tranexamic acid (TXA), bipolar sealer electrocautery, and topical hemostatic agents, and hypotensive anesthesia (mean arterial pressure (MAP) <65 mm Hg) should be strongly considered in cases with larger exposures and higher anticipated blood loss. There is strong level 1 evidence for the use of TXA in spine surgery as it reduces the overall blood loss and transfusion requirements. Conclusion: As the volume and complexity of spinal procedures rise, intraoperative blood loss management has become a pivotal topic of research within the field. There are many tools for minimizing blood loss in patients undergoing spine surgery. The current literature supports combining techniques to use a cost- effective multimodal approach to minimize blood loss in the perioperative period.

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Section: Topical Hemostatic Agentsmentioning

confidence: 99%

Minimizing Blood Loss in Spine Surgery

Mikhail

Pennington

Arnold

et al. 2020

Global Spine Journal

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show abstract

“…Absorptive gelatin sponge is a semi-synthetic material. Its unique sponge-like structure has protective effects on nerve roots [ 12 ], and its collagen properties have a good effect on preventing adhesions around the dura mater and nerve roots after decompression [ 13 ]. At the same time because of its good hemostatic effect is often used in spinal surgery.…”

Section: Discussionmentioning

confidence: 99%

Intraoperative anti-inflammatory drugs combined with no drainage after MIS-TLIF in the treatment of recurrent lumbar disc herniation: an RCT

et al. 2021

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Background Minimally invasive-transforaminal lumbar interbody fusions (MIS-TLIF), in which the nerve root pain is caused by early postoperative edema reaction, is a common clinical complication. However, there is no effective method to solve this problem. We aimed to use gelatin sponge impregnated with mixed anti-inflammatory drugs combined with no drainage after MIS-TLIF to optimize postoperative effect in the treatment of recurrent lumbar disc herniation (LDH). Methods From June 2018, the middle-aged patients (45–60 years old) with recurrent LDH were recruited. Included patients were treated with MIS-TLIF surgery, and no drainage tube was placed after surgery. All patients were randomly divided into intervention group (gelatin sponge impregnated with mixed anti-inflammatory drugs) and control group (saline was immersed in gelatin sponge as a control). Results The intervention group included 63 cases, and the control group included 65 cases. The length of hospital stays and bedridden period in the intervention group were significantly lower than those in the control group (P < 0.05). The VAS score of low back pain in the intervention group was significantly lower than that of the control group at postoperative days 1–6 (P < 0.05, for all). The VAS scores of leg pain in the intervention group at postoperative days 1–9 were statistically lower than the control group (P < 0.05, for all). Conclusions Application of gelatin sponge impregnated with mixed anti-inflammatory drugs combined with no drainage after MIS-TLIF can significantly further optimize the surgical effect of recurrent LDH and shorten the bedridden period and hospital stays, to achieve the purpose of early rehabilitation. Trial registration China Clinical Trial Registration Center, ChiCTR1800016236. Registered on May 21, 2018, http://www.chictr.org.cn/listbycreater.aspx

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“…Absorptive gelatin sponge is a semi-synthetic material. Its unique sponge-like structure has protective effects on nerve roots (12), and its collagen properties have a good effect on preventing adhesions around the dura mater and nerve roots after decompression (13). At the same time because of its good hemostatic effect is often used in spinal surgery.…”

Section: Discussionmentioning

confidence: 99%

Intraoperative Anti-Inflammatory Drugs Combined With No Drainage After MIS-TLIF in the Treatment of Recurrent Lumbar Disc Herniation: An RCT

Yang

Yan

et al. 2020

Preprint

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Background. Minimally Invasive-Transforaminal Lumbar Interbody Fusions (MIS-TLIF), in which nerve root pain caused by early postoperative edema reaction is a common clinical complication. However, there is no effective method to solve this problem. We aimed to use gelatin sponge impregnated with mixed anti-inflammatory drugs combined with no drainage after MIS-TLIF to optimize postoperative effect in the treatment of recurrent lumbar disc herniation (LDH).Methods. From June 2018, the middle-aged patients (45-60 years old) with recurrent LDH were recruited. Included patients were treated with MIS-TLIF surgery, no drainage tube was placed after surgery. All patients were randomly divided into intervention group (Gelatin sponge impregnated with mixed anti-inflammatory drugs) and control group (Saline was immersed in gelatin sponge as a control). Results. The intervention group included 63 cases and the control group included 65 cases. The length of hospital stays and bedridden period in the intervention group were significantly lower than those in the control group (P<0.05). The VAS score of low back pain in the intervention group was significantly lower than that of the control group at postoperative day 1-6 (P<0.05, for all). The VAS scores of leg pain in the intervention group at postoperative day 1-9 were statistically lower than the control group (P<0.05, for all). Conclusions. Application of gelatin sponge impregnated with mixed anti-inflammatory drugs combined with no drainage after MIS-TLIF can significantly further optimize the surgical effect of recurrent LDH, shorten the bedridden period and hospital stays, to achieve the purpose of early rehabilitation.Trial registration: China Clinical Trial Registration Center, ChiCTR1800016236. Registered 21 May 2018, http://www.chictr.org.cn/listbycreater.aspx

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Comparison the efficacy of hemorrhage control of Surgiflo Haemostatic Matrix and absorbable gelatin sponge in posterior lumbar surgery

Cited by 29 publications

References 17 publications

Minimizing Blood Loss in Spine Surgery

Minimizing Blood Loss in Spine Surgery

Intraoperative anti-inflammatory drugs combined with no drainage after MIS-TLIF in the treatment of recurrent lumbar disc herniation: an RCT

Intraoperative Anti-Inflammatory Drugs Combined With No Drainage After MIS-TLIF in the Treatment of Recurrent Lumbar Disc Herniation: An RCT

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