Comparison study of hydrophilic contact lens surfactant cleaners: A clinical evaluation of residual deposits

Reindel, William; Ploscowe, Vicki; Minno, George; Burke, James H.; Castellano, Carmen; Hood, Donald W.; Piccolo, Marc; Snyder, Christopher W.; Steel, Scott A.; Welcker, Stephen

doi:10.1016/0892-8967(89)90038-2

Cited by 7 publications

(1 citation statement)

References 7 publications

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“…The surfactants currently used in commercial contact lens care solutions are mainly poloxamer (F127), polyethylene glycol-400 (PEG-400), and polyoxyethylene castor oil (EL-35). However, these surfactants have low clearance ability for tear proteins [17,18]. In addition, the PEG-400 has potential side effects such as vision loss, cataract formation, retinal degeneration, and detachment after PEG-400 injection in the retina or vitreous [19,20].…”

mentioning

confidence: 99%

Low molecular weight chitosan oligosaccharides form stable complexes with human lactoferrin

Li,

Guan,

Cai

et al. 2023

FEBS Open Bio

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Proteins in tears, including human lactoferrin (HLF), can be deposited and denatured on contact lenses, increasing the risk of microbial cell attachment to the lens and ocular complications. The surfactants currently used in commercial contact lens care solutions have low clearance ability for tear proteins. Chitosan oligosaccharide (COS) binds to a variety of proteins, and has potential for use in protein removal, especially in contact lens care solutions. Here, we analyzed the interaction mechanism of COSs hydrolyzed from chitosan from different resources with HLF. The molecular weights (MWs) and concentrations of COSs were key factors for the formation of COS‐HLF complexes. Lower MWs of COSs could form more stable COS‐HLF complexes. COS from Aspergillus ochraceus had a superior effect on HLF compared with COS from shrimp and crab shell with the same MWs. In conclusion, COSs could bind to and cause a conformational change in HLF. Therefore, COSs, especially those with low MWs, have potential as deproteinizing agents in contact lens care solution.

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mentioning

confidence: 99%

Low molecular weight chitosan oligosaccharides form stable complexes with human lactoferrin

Li,

Guan,

Cai

et al. 2023

FEBS Open Bio

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Ophthalmological Preparations

Dolak¹,

Lever²,

Marsh³

et al. 2000

Ullmann's Encyclopedia of Industrial Chemistry

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The article contains sections titled: 1. Introduction 2. Anesthetics 2.1. Topical Anesthetics 2.2. Regional Anesthetics 3. Antimicrobial Agents 3.1. Antibacterial Agents 3.1.1. Sulfonamides 3.1.2. β‐Lactam Antibiotics 3.1.2.1. Penicillins 3.1.2.2. Cephalosporins 3.1.3. Tetracycline Antibiotics 3.1.4. Aminoglycoside Antibiotics 3.1.5. Polypeptide Antibiotics 3.1.6. Miscellaneous Antimicrobial Agents 3.2. Antifungal Agents 3.3. Antiprotozoal Agents 3.4. Antiviral Agents 4. Anti‐inflammatory Agents 4.1. Corticosteroids 4.2. Miscellaneous Anti‐inflammatory Agents 5. Antiglaucomatous Agents 5.1. Sympathomimetic Drugs 5.2. β‐Adrenergic Blocking Agents 5.3. Carbonic Anhydrase Inhibitors 5.4. Hyperosmotic Agents 5.5. Miotics (Parasympathomimetic Agents) 5.5.1. Cholinergic Agonists 5.5.2. Anticholinesterases 6. Mydriatics and Cycloplegics 6.1. Sympathomimetics 6.2. Parasympatholytics 7. Vasoactive (Adrenergic) Agents 8. Diagnostic Agents 9. Dry Eye Medications 10. Miscellaneous Ophthalmic and Contact Lens Preparations 10.1. Disinfectants and Preservatives 10.1.1. Biguanides 10.1.2. Mercurial Preservatives 10.1.3. Quaternary Ammonium Compounds 10.1.4. Miscellaneous Disinfectants and Preservatives 10.2. Contact Lens Cleaners and Rewetting Agents 10.2.1. Surfactant Cleaners 10.2.2. Enzymatic Cleaners

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Evaluation of the relationship between total lens protein deposition and patient-rated comfort of hydrophilic (soft) contact lenses

Lever¹,

Groemminger²,

Allen³

et al. 1995

International Contact Lens Clinic

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Comparison study of hydrophilic contact lens surfactant cleaners: A clinical evaluation of residual deposits

Cited by 7 publications

References 7 publications

Low molecular weight chitosan oligosaccharides form stable complexes with human lactoferrin

Low molecular weight chitosan oligosaccharides form stable complexes with human lactoferrin

Ophthalmological Preparations

Evaluation of the relationship between total lens protein deposition and patient-rated comfort of hydrophilic (soft) contact lenses

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