Comparison of X-rays and magnetic resonance imaging in the definition of tibiofemoral joint osteoarthritis

Glisson, Michael; Forbes, Andrew Benjamin; Morris, Kevin; Stuckey, Stephen; Cicuttini, Flavia Maria

doi:10.1053/radi.2000.0258

Radiography

2000

DOI: 10.1053/radi.2000.0258

|View full text |Cite

Comparison of X-rays and magnetic resonance imaging in the definition of tibiofemoral joint osteoarthritis

Michael Glisson¹,

Andrew Benjamin Forbes²,

Kevin Morris³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2001

2004

Publication Types

Select...

Article6

Relationship

Self Cite1

Independent5

Authors

Journals

Cited by 10 publications

(2 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Magnetic resonance imaging (MRI) is a simple, safe, non-invasive, and reproducible technique for measuring knee cartilage thickness and volume in vivo 12-15. Cartilage volume measured by MRI correlates well with radiological grading of joint space narrowing, in both the lateral and medial femoral compartments 16. A diurnal variation in the thickness, but not volume (both measured by MRI), of normal femoral articular cartilage related to prolonged weight bearing has been shown 17.…”

mentioning

confidence: 87%

Users of oestrogen replacement therapy have more knee cartilage than non-users

Wluka

Davis

Bailey

et al. 2001

Annals of the Rheumatic Diseases

184

146

View full text Add to dashboard Cite

Background-Osteoarthritis (OA) is increasingly prevalent in the years after menopause. Epidemiological data suggest that the use of oestrogen replacement therapy (ERT) may protect against knee OA. Aim-To test the hypothesis that long term ERT (longer than five years) is associated with increased knee cartilage in postmenopausal women. Methods-The study involved 81 women (42 current users (> five years) of ERT and 39 who had never used it). Articular cartilage volumes were determined by processing images acquired in the sagittal plane using a T1 weighted fat suppressed magnetic resonance sequence on an independent work station. Results-After bone size had been accounted for, ERT users had higher tibial cartilage volume than non-users. Total tibial cartilage volume was 7.7% (0.23 ml) greater in the group of ERT users (2.98 (0.47) ml; mean (SD)) than in the untreated group (2.75 (0.50) ml). The diVerence, after adjustment for the significant explanatory factors (years since menopause, body mass index, age at menopause, and smoking), between the ERT users and non-users increased from 0.23 ml to 0.30 ml (95% confidence interval 0.08 to 0.52, p=0.008). These diVerences persisted after exclusion of women with OA. Conclusions-After adjustment for multiple confounders, women using long term ERT have more knee cartilage than controls. This may indicate that ERT prevents loss of knee articular cartilage. (Ann Rheum Dis 2001;60:332-336) Osteoarthritis (OA) is the major cause of disability in people over 65. 1No known treatment aVects its progression. It is more common in women than men, suggesting that diVerences in sex hormones modulate the disease. However, the eVect of oestrogen replacement therapy (ERT) on the incidence and prevalence of OA in postmenopausal women is controversial. Few epidemiological studies on the eVect of ERT on the prevalence of OA have produced statistically significant results. [2][3][4]

show abstract

mentioning

confidence: 87%

Users of oestrogen replacement therapy have more knee cartilage than non-users

Wluka

Davis

Bailey

et al. 2001

Annals of the Rheumatic Diseases

184

146

View full text Add to dashboard Cite

show abstract

“…This is important in longitudinal studies. Cartilage volume has been shown to correlate with radiographic grade of OA (15). It is possible that articular cartilage volume may be a useful measure for disease progression in OA.…”

mentioning

confidence: 99%

The determinants of change in tibial cartilage volume in osteoarthritic knees

Wluka¹,

Stuckey²,

Snaddon³

et al. 2002

Arthritis & Rheumatism

Self Cite

228

242

View full text Add to dashboard Cite

Objective. The rate of change in osteoarthritic (OA) tibial articular cartilage and the factors that influence it are not known. We examined a cohort of subjects with OA to determine the change in articular knee cartilage volume over the course of 2 years and to identify factors which might influence such change and its rate.Methods. One hundred twenty-three subjects with OA underwent baseline knee radiography and magnetic resonance imaging (MRI) on their symptomatic knee. They were followed up 2 years later with a repeat MRI of the same knee. Knee cartilage volume was measured at baseline and at followup. Risk factors assessed at baseline were tested for their association with change in knee cartilage volume over time.Results. Mean ؎ SD total tibial articular cartilage decreased by 5.3 ؎ 5.2% (95% confidence interval [95% CI] 4.4%, 6.2%) per year. The annual percentages of loss of medial and lateral tibial cartilage were 4.7 ؎ 6.5% (95% CI 3.6%, 5.9%) and 5.3 ؎ 7.2% (95% CI 4.1%, 6.6%), respectively. Initial cartilage volume was the most significant determinant of loss of tibial cartilage in all compartments, while age was a significant determinant of lateral tibial cartilage loss, when possible confounders were accounted for.Conclusion. In OA, tibial cartilage volume is lost at a rate of ϳ5% per year. The main factor affecting cartilage loss is initial cartilage volume. Our results suggest that cartilage loss may be more rapid early in disease. Further study is required to determine whether the rate of cartilage loss in OA is steady or phasic, and to identify factors amenable to intervention to reduce cartilage loss.

show abstract

The effect of scan acquisition plane on the perceived quality of T1 weighted three-dimensional MR reconstructions of bony knee anatomy

2004

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Comparison of X-rays and magnetic resonance imaging in the definition of tibiofemoral joint osteoarthritis

Cited by 10 publications

References 8 publications

Users of oestrogen replacement therapy have more knee cartilage than non-users

Users of oestrogen replacement therapy have more knee cartilage than non-users

The determinants of change in tibial cartilage volume in osteoarthritic knees

The effect of scan acquisition plane on the perceived quality of T1 weighted three-dimensional MR reconstructions of bony knee anatomy

Contact Info

Product

Resources

About